A synthesis to access rarely described 3-amino-5-fluoroalkylfurans has been developed by cyclization of easily accessible fluorovinamides. This method is rapid and simple affords the desired furans as hydrochloride salts in quantitative or nearly yields. It compatible with four different fluorinated groups (-CF3, -CF2CF3, -CHF2, -CF2Cl) a wide range substituents on amine.

The title compound, C(18)H(18)N(4)OS, has an almost planar 1,2,4-triazole ring [r.m.s. deviation = 0.0036 (2) Å], which makes dihedral angles of 78.5 (2) and 77.6 (11)° with the two phenyl rings. An intra-molecular N-H⋯S inter-action occurs. In the crystal, mol-ecules are linked by an inter-molecular three-centre N-H⋯(O,S) cyclic hydrogen-bonding inter-action.

The title compound, C(17)H(17)N(5)O, exists in the zwitterionic form with the amide group deprotonated. The mean planes of the 1,2,4-triazole and N-phenyl rings form a dihedral angle of 39.14 (8)°. The N atom of the amino group adopts a trigonal configuration. Inter-moleculat C-H⋯O and C-H⋯N hydrogen bonds occur. In the crystal, mol-ecules are linked into a two-dimensional network parallel to (...