OBJECTIVE To study the influence of obstructive sleep apnea (OSA) on 24-h BP. SETTING Sleep laboratory of the Medical Department, Neukölln Hospital, Berlin, Germany. METHODS In 93 subjects, noninvasive 24-h BP monitoring was performed with BP recordings made at 15-min intervals. Apnea severity was evaluated by means of a portable device that allows calculation of an oxygen desaturation inde...

The objective was to examine the association between high blood pressure (BP) and chronic daily headache using 24-h ambulatory blood pressure monitorization (24-h ABPM). This was a cross sectional study in an out-patient clinic. Women were selected among patients referred for first evaluation, 62 with chronic daily headache and 57 without chronic daily headache. The main outcome measures were m...

Available evidence suggests that both homocysteine and blood pressure variability (BPV) are closely correlated with cardio-cerebrovascular disease. However, no previous study has addressed the correlation between homocysteine levels and 24-h ambulatory BPV. The aim of this study was to investigate the relationship between serum homocysteine levels and 24-h ambulatory BPV in Chinese hypertensive...

BACKGROUND AND PURPOSE High blood pressure (BP) is associated independently with poor outcome after acute ischemic stroke, although in most analyses "baseline" BP was measured 24 hours or more postictus, and not during the hyperacute period. METHODS Analyses included 1722 patients in hyperacute trials (recruitment <8 hours) from the Virtual Stroke International Stroke Trial Archive (VISTA) Co...

To document the correlation between renal damage and circadian blood pressure variation, urinary microalbumin excretion rate (UAER) and 24-hour ambulatory blood pressure monitoring (24-hr ABPM) were performed in 16 normotensives and 29 stage I-III essential hypertensive subjects (whole-day mean BP; 120.13/79.06 mmHg vs 152.59/94.31 mmHg, p < 0.05). The BP variables of 24-hr ABPM included hourly...

BACKGROUND In high-cardiovascular-risk treated hypertensive patients, the incidence of cardiovascular events has been reported to relate to visit-to-visit blood pressure (BP) variability. We investigated whether visit-to-visit BP variability is prognostically important in treated mildly to moderately hypertensive patients in whom treatment aims at avoiding events but also at preventing or delay...

Background—In high-cardiovascular-risk treated hypertensive patients, the incidence of cardiovascular events has been reported to relate to visit-to-visit blood pressure (BP) variability. We investigated whether visit-to-visit BP variability is prognostically important in treated mildly to moderately hypertensive patients in whom treatment aims at avoiding events but also at preventing or delay...

BACKGROUND The aim of this study was to compare the antihypertensive efficacy of losartan 100 mg + hydrochlorothiazide (HCTZ) 25 mg versus bisoprolol 10 mg + HCTZ 25 mg and their influence on arterial stiffness and central blood pressure (BP). METHODS Of 60 patients with a mean BP of 173.3 ± 1.7/98.4 ± 1.2 mmHg, 59 were randomized to losartan + HCTZ (n = 32) or bisoprolol + HCTZ (n = 27). Aml...

Hereditary neuralgic amyotrophy (HNA) is an autosomal dominant disorder associated with recurrent episodes of focal neuropathy primarily affecting the brachial plexus. Point mutations in the SEPT9 gene have been previously identified as the molecular basis of HNA in some pedigrees. However in many families, including those from North America demonstrating a genetic founder haplotype, no sequenc...

BACKGROUND The relationship between sodium intake and blood pressure (BP) is affected by many factors such as absolute level of sodium intake, salt sensitivity, and the accuracy or the timing of the BP measurement. There is no epidemiologic study using both ambulatory BP monitoring (ABPM) and 24-h urine sample in a middle-aged general population. METHODS In the rural area, Yeojoo County, Gyun...