The remarkable scientific work on fertility preservation that is documented in the early chapters of this volume will inevitably give rise to moral and religious questions about the use of technology to reproduce. In this regard, oncofertility is no different from other forms of assisted reproduction that have led to extensive debate among ethicists and moral theologians. In the case of many fo...

Background. There is a need in primary care for simple asthma outcome measures that are valid in terms of their relationship with lung function and capable of predicting those patients for whom additional management is indicated. Aim. To assess the predictive validity of a revised asthma morbidity index in United Kingdom (UK) general practice. Method. Morbidity index and peak flow rate data wer...

OBJECTIVE Psychotherapy research may suffer from factors such as a researcher's own therapy allegiance. The aim of this study was to evaluate if researcher allegiance (RA) was reported in meta-analyses and randomised controlled trials (RCTs) of psychotherapeutic treatments. DESIGN Systematic approach using meta-analyses of different types of psychotherapies. DATA SOURCES Medline, PsycINFO a...

BACKGROUND/AIM This study aimed to identify IDUA gene mutations in Turkish patients morphologically (phenotypic) diagnosed with MPS type I. It also sought to discuss the possible effects of detected mutations on alpha-L-iduronidase enzyme function based on current knowledge. MATERIALS AND METHODS Genetic analysis was carried out in 15 patients using direct DNA sequencing. Moreover, segregatio...

OBJECTIVE Hepatitis C virus (HCV) infection is a high morbidity disease in China. The aim of this study was to explore the latest distribution of HCV genotypes in China, mainly focusing on epidemiological characteristics and risk factors of HCV genotype 1 in Chinese Han population. PATIENTS AND METHODS 793 HCV-positive patients were enrolled from 21 hospitals across China. The association of ...

It is an unfortunate fact of academic life that there is a sharp divide between science and philosophy, with scientists often being openly dismissive of philosophy, and philosophers being equally contemptuous of the naiveté of scientists when it comes to the philosophical underpinnings of their own discipline. In this paper I explore the possibility of reducing the distance between the two side...