نتایج جستجو برای: 224
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This editorial refers to Myeloperoxidase, but not C-reactive protein, predicts cardiovascular risk in peripheral arterial disease by G. Brevetti et al., on page 224.
با پیروزی اردشیر یکم ساسانی (240-224 م) بر اردوان چهارم اشکانی (224-213 م) در نبرد هرمزگان در 224 میلادی، شاهنشاهی ساسانی در تاریخ پدیدار شد. دو پادشاه نخستین ساسانی، اردشیر یکم و شاپور یکم (272 – 240 م)، که اکنون بر ایران و بین النهرین سیطره یافته بودند، بر آن شدند تا تصور و تصویری از پیدایی و پایداری این شاهنشاهی بزرگ را بر همگان ارائه کنند. جانشینان شاپور تا نرسی، این هدف را ادامه دادند که د...
BACKGROUND HBV and HCV reactivation have been widely reported in patients undergoing immunosuppressive therapy (IT); however, few data are available on the risk of reactivation in patients with psoriasis receiving IT. The aim of our study was to assess the prevalence of HBV and HCV infection in patients with psoriasis and to evaluate the effects of IT during the course of the infection. METHO...
Superoxide dismutase 1 (SOD1) is an abundant copper/zinc enzyme found in the cytoplasm that converts superoxide into hydrogen peroxide and molecular oxygen. Tetrathiomolybdate (ATN-224) has been recently identified as an inhibitor of SOD1 that attenuates FGF-2- and VEGF-mediated phosphorylation of ERK1/2 in endothelial cells. However, the mechanism for this inhibition was not elucidated. Growth...
The recognition of methionine as an important building stone of the protein molecule is one of the most significant advances in our knowledge of the chemistry of the biologically important sulfur compounds (1). Methionine has been shown to function similarly to cystine both for purposes of growth in rats fed a diet inadequate in its cystine content (2) and for the detoxication of monobromobense...
WS9326A binds competitively to [3H]substance P (NK-1 receptor) binding sites on guinea-pig lung membranes (IC50 = 3.6 x 10(-6) M), and acts as a tachykinin antagonist in various functional assays. WS9326A inhibited tracheal constrictions produced by exogenously added substance P and neurokinin A, with IC50 values of 9.7 x 10(-6) M and 3.5 x 10(-6) M, respectively. WS9326A inhibited neurokinin A...
The aim of this study was to elucidate the role of thromboxane A(2) (TxA(2)) on asthma-related cough in guinea pigs. Animals were immunosensitized and repeatedly challenged with ovalbumin as an antigen. Coughs were induced by the inhalation of 10(-5) M capsaicin solution for 10 min. Thromboxane synthetase (TxS) inhibitor OKY-046 and thromboxane-receptor antagonist AA-2414 significantly inhibite...
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