Proverbs are Words of Wisdom, uttered traditionally, expressing some perceived truth based on common sense or Human Experiences. bears Ironic and Metaphorical Nature used in Formulaic Structure Languge. This unique Genre Folklore enhances the Wisdom Literature. As Lamps Speech Strategies to deal with Situations, that is why, for them, it necessary have a memorizable Sentence Structures. Studies...

222 donor and 222 acceptor (including 206 pairs) non-homologous splicing sites were studied. Well known features of these were confirmed and some novel observations were made. It is (1) cCAGGGag signal in (-60)-(-58) region of acceptor sites; (2) strong complementarity between regions (-69)-(-55) and (-36)-(-22) of some of the acceptor sites, and (3) small but statistically significant correlat...

Running Head: Maternal infection induces cytokines in fetal environment All correspondence to: Dave A. Gayle, Ph.D. Department of Obstetrics and Gynecology, Harbor-UCLA Medical Center and Research and Education Institute, RB-1, Box 446, Torrance, CA 90502. Phone: 310-222-1976; Fax: 310-222-4131; email: [email protected] Acknowledgements: This work was supported by funding from NIH RO1 DK43311 and...

ZnFe2O4 (ZFO) thin films exhibiting varying crystallographic features ((222)-epitaxially, (400)-epitaxially, and randomly oriented films) were grown on various substrates by radio-frequency magnetron sputtering. The type of substrate used profoundly affected the surface topography of the resulting ZFO films. The surface of the ZFO (222) epilayer was dense and exhibited small rectangular surface...

The analysis of a microRNA (miRNA), miR-222 isolated from the PC12 cell line, was performed by use of the ribonuclease (RNase) protection assay, cyanine 5 (Cy5)-labeled miR-222 riboprobe, and a Hitachi SV1210 microchip electrophoresis system, which can be used to evaluate the integrity of total RNA. The fluorescence intensity corresponding to the protected RNA fragment increased in a dose-depen...

Variability of the bony structures located in the maxillary sinus, and of the lateral nasal wall topography, have practical significance during surgical procedures conducted by maxillofacial surgeons or otolaryngologists. The retrospective analysis of 111 computed tomography examinations of patients (52 male and 59 female) diagnosed in our institution was made to evaluate anatomical variations ...

The most critical stage in initiation of melanoma metastasis is the radial to vertical growth transition, yet the triggers of this transition remain elusive. We suggest that the microenvironment drives melanoma metastasis independently of mutation acquisition. Here we examined the changes in microenvironment that occur during melanoma radial growth. We show that direct contact of melanoma cells...

The mismatch repair system (MMR) is a post-replicative DNA repair mechanism whose defects can lead to cancer. The MSH3 protein is an essential component of the system. We postulated that MSH3 gene polymorphisms might therefore be associated with prostate cancer (PC). We studied MSH3 codon 222 and MSH3 codon 1036 polymorphisms in a group of Iranian sporadic PC patients. A total of 60 controls an...

The present study was aimed at investigating the analgesic properties of a combination of lidocaine and QX-222 and its effects on evoked pain behavior (complete Freund's adjuvant-induced allodynia and hyperalgesia in inflammatory condition) and spontaneous pain behavior (formalin-induced acute pain) in mice. Drugs were injected adjacent to sciatic nerve or into plantar. Motor function, thermal ...

A variety of extracellular signals lead to the phosphorylation and activation of mitogen-activated protein kinases (MAP kinases). An activator of MAP kinases, Mek1, phosphorylates MAP kinases at threonine and tyrosine residues and is itself phosphorylated at serine-218 and -222 by the protooncogene product Raf-1. By introducing negatively charged residues that may mimic the effect of phosphoryl...