Seventy-six thallium-201 myocardial perfusion studies were performed on twenty-five patients to assess their reproducibility and the effect ofvarying the level of exercise on the results of imaging. Each patient had a thallium-201 study at rest. Fourteen patients had studies on two occasions at maximum exercise, and twelve patients had studies both at light and at maximum exercise. Of 70 segmen...

We study the effects of diverse team composition on the survival and growth of new ventures using the Danish Linked Employer-Employee database. To get cleaner measures of diverse team composition, we focus on entrepreneurial dyads, and also investigate the asymmetric effects of team composition by distinguishing between the ‘primary’ and the ‘secondary’ founder. We complement existing work by s...

Background: Serious concern has been raised about the sustainability of public health care systems of European Nations and ultimately about the health of European citizens, as a result of the economic crisis that has distressed Europe since 2008. The severe economic crisis of the Euro zone, which is still afflicting Europe in 2016, has in fact threatened to equally impact public health services...

BACKGROUND It is widely known that blood flow redistribution is impaired in patients with chronic heart failure (CHF). However, the relationship between exercise tolerance and the degree of blood flow redistribution is not fully understood. Whole-body thallium-201 chloride ((201)Tl) scintigraphy can estimate blood flow distribution. This study will evaluate the relationship between exercise tol...

OBJECTIVE To evaluate the usefulness of (201)Tl-SPECT in differentiating benign from malignant brain tumors. METHODS AND MATERIALS Eighty-eight patients (44 males and 44 females) with 58 high-grade (WHO grade III-IV) and 30 low-grade (WHO grade I-II) tumors were evaluated with (201)Tl-SPECT. (1) Visual assessment was performed by board-certificated radiologists using (201)Tl-SPECT. Tumors wer...

RATIONALE At physiologic pressures, elastic fibers constrain artery diameter. Local treatment of atherosclerotic arteries with PRT-201, a recombinant type I elastase, could result in fragmentation and removal of elastin fibers and increased vessel diameter. OBJECTIVE To investigate the use of PRT-201 as a treatment for human atherosclerotic arteries. METHODS AND RESULTS Arteries were harves...

1 Department of Chemical Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028-1701 2 Department of Civil and Environmental Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028-1701 3 Department of Chemical Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, New Jersey 08028-1701 4 Department of Chemical Engineering, Rowan Un...

Backgrounds: Thallium-201 is produced through 203Tl (p, 3n) 201pb 201Tl reaction by cyclotron. This radioisotope has known as one of the cyclotron radioisotopes which is used for myocardial perfusion in the coronary artery disease, Tl-201 after chemical purification and quality control in the form of 201Tl-chlorid is ready to send to the hospitals. Materials and methods: In this work the effect...

OBJECTIVES The aim of this study was to compare the myocardial retention of technetium-99m (Tc-99m) sestamibi and thallium-201 over a wide range of blood flow at different time points after tracer injection. BACKGROUND Technetium-99m sestamibi has been proposed as a new perfusion tracer with better physical characteristics than those of thallium-201 for scintigraphic imaging. However, no stud...

PURPOSE To explore the safety and efficacy of PRT-201 applied to the outflow vein of a newly created arteriovenous graft (AVG). METHODS Randomized, double-blind, placebo-controlled, single-dose escalation study of PRT-201 (0.01 to 9 mg) applied to the graft-vein anastomosis and adjacent outflow vein immediately after AVG placement. The primary outcome measure was safety. The efficacy measures...