نتایج جستجو برای: 20 oc

تعداد نتایج: 619153  

Journal: :BJU international 2010
Sascha A Ahyai Mario Zacharias Hendrik Isbarn Thomas Steuber Christian Eichelberg Jens Köllermann Margit Fisch Pierre I Karakiewicz Hartwig Huland Markus Graefen Felix K-H Chun

OBJECTIVE To identify risk factors of a positive surgical margin (PSM) and the significance of a PSM after radical prostatectomy (RP) on biochemical recurrence (BCR) in exclusively pathologically confirmed organ-confined (OC) prostate cancer, as despite an excellent prognosis after RP, some patients with pathologically confirmed OC disease have BCR, and the prognostic significance of a PSM in t...

Journal: :Obstetrics and gynecology 2005
Anne Rachel Davis Carolyn Westhoff Katharine O'Connell Nancy Gallagher

OBJECTIVE To assess whether a low-dose oral contraceptive (OC) is more effective than placebo treatment for dysmenorrhea pain in adolescents. METHODS This was a randomized, double-blind, placebo-controlled clinical trial of 76 healthy adolescents aged 19 years or younger reporting moderate or severe dysmenorrhea. Subjects were randomly allocated to receive either an OC (ethinyl estradiol [E2]...

2016
Andreas Rump Anna Benet-Pages Steffen Schubert Jan Dominik Kuhlmann Ramūnas Janavičius Eva Macháčková Lenka Foretová Zdenek Kleibl Filip Lhota Petra Zemankova Elitza Betcheva-Krajcir Luisa Mackenroth Karl Hackmann Janin Lehmann Anke Nissen Nataliya DiDonato Romy Opitz Holger Thiele Karin Kast Pauline Wimberger Elke Holinski-Feder Steffen Emmert Evelin Schröck Barbara Klink

The increasing application of gene panels for familial cancer susceptibility disorders will probably lead to an increased proposal of susceptibility gene candidates. Using ERCC2 DNA repair gene as an example, we show that proof of a possible role in cancer susceptibility requires a detailed dissection and characterization of the underlying mutations for genes with diverse cellular functions (in...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2013
Nora Lee Mary F Hebert Bhagwat Prasad Thomas R Easterling Edward J Kelly Jashvant D Unadkat Joanne Wang

Polyspecific organic cation (OC) transporters play important roles in the disposition of clinically used drugs, including drugs used during pregnancy. Pregnancy is known to alter the expression of drug-metabolizing enzymes and transporters, but its specific effect on OC transporters has not been well defined. Using quantitative polymerase chain reaction and liquid chromatography coupled with ta...

2015
Cristian Gudasz Sebastian Sobek David Bastviken Birgit Koehler Lars J. Tranvik

Temperature alone explains a great amount of variation in sediment organic carbon (OC) mineralization. Studies on decomposition of soil OC suggest that (1) temperature sensitivity differs between the fast and slowly decomposition OC and (2) over time, decreasing soil respiration is coupled with increase in temperature sensitivity. In lakes, autochthonous and allochthonous OC sources are general...

Journal: :Blood 2007
Maria K Johansson Teun J de Vries Ton Schoenmaker Mats Ehinger Ann C M Brun Anders Fasth Stefan Karlsson Vincent Everts Johan Richter

Infantile malignant osteopetrosis (IMO) is a fatal disease caused by lack of functional osteoclasts, and the only available treatment is hematopoietic stem cell (HSC) transplantation. In the majority of patients, the TCIRG1 gene, coding for a subunit of a proton pump essential for bone resorption, is mutated. Oc/oc mice have a deletion in the homologue gene (tcirg1) and die at 3 to 4 weeks, but...

2017
Walter E. Dean Eville Gorham

Globally, lakes are currently accumulating organic carbon (OC) at an estimated annual rate of about 42 Tg·yr. Most of the OC in all but the most oligotrophic of these lakes is autochthonous, produced by primary production in the lakes. The sediments of reservoirs accumulate an additional 160 Tg annually, and peatlands contribute 96 Tg annually. These three carbon pools collectively cover less t...

1997
Haoran Duan John W. Lockwood Sung-Mo Kang J. D. Will

This paper presents the design and prototype of an intelligent, 3-Dimensional-Queue (3DQ) for highperformance, scalable, input bu ered ATM switches. 3DQ uses pointers and linked lists to organize ATM cells into multiple virtual queues according to priority, destination, and virtual connection. It enforces per virtual connection Quality-of-Service (QoS) and eliminates Head-Of-Line (HOL) blocking...

2010

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2011

High-latitude regions store large amounts of organic carbon (OC) in active-layer soils and permafrost, accounting for nearly half of the global belowground OC pool. In the boreal region, recent warming has promoted changes in the fire regime, which may exacerbate rates of permafrost thaw and alter soil OC dynamics in both organic and mineral soil. We examined how interactions between fire and p...

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