The structures of three 3-methyl-1H-1,2,4-triazole-5-thione derivatives are reported. The structure of 4-amino-3-methyl-1H-1,2,4-triazole-5(4H)-thione, C3H6N4S, (I), has been redetermined with an improved model for the H atoms: the non-H atoms of (I) all lie on mirror planes in space group Pbcm, and the H atoms of the methyl group are disordered over two sets of reflection-related atomic sites ...

The title compound, C9H12N2OS4·0.5C6H5Cl, which contains two 1,3-thia-zolidine-2-thione rings, is a by-product of the synthesis of 3-acryloyl-1,3-thia-zolidine-2-thione. The dihedral angle between these rings is 79.95 (9)°, with both rings displaying a twisted conformation. The twist angle of the amide group is 5.6 (1)°. In the crystal, the molecules are linked into [001] chains by C-H⋯O intera...

The molecular structures of two Pyridazine derivative;5-phenyl-6-ethyl-pyridazine-3-thione (PEPT) and 5-phenyl-6-ethylpridazine-3-one (PEPO) were simulated for corrosion inhibition efficiency using quantum chemical calculations based on density functional theory (DFT) at the B3LYP/6-31G* basis set level in order to compare relationship between their structure,electronic structure potential.The ...

The facile regioselective synthesis of the P(iii) substituted thiazol-2-thione 2 is presented. Reaction of 2 with hydrogenperoxide-urea, elemental sulfur and selenium resulted in P(v) chalcogenide thiazol-2-thiones 3-5. All compounds were characterized using (31)P, (1)H, (13)C NMR, IR and elemental analyses and, additionally, by the single-crystal X-ray diffraction technique. Oxidative desulfur...

A kinematic approach was used to measure mother-infant spatial proximity at 4 months. Maternal postpartum depression (PPD) impacts on mother-infant spatial interaction. We compared 28 dyads with mothers meeting criteria for PPD and 46 typical dyads. The PPD dyads had less variability in spatial proximity compared to typical dyads.

A straightforward general synthetic access to N-aryl-1,3-dithiolo[4,5-c]pyrrole-2-thione derivatives 6 from acetylenedicarbaldehyde monoacetal is depicted. In addition to their potentiality as precursors to dithioalkyl-pyrrole derivatives, thiones 6 are key building blocks to N-aryl monopyrrolo-tetrathiafulvalene (MPTTF) derivatives 10. X-ray structures of four of these thiones intermediates, r...

Abstract The oxidation of various non‐S‐oxidized 4 H ‐1,2,6‐thiadiazines with N 2 O , meta ‐chloroperbenzoic acid ( m ‐CPBA), Oxone, [bis(trifluoroacetoxy)iodo]benzene (PIFA) and phenyliodine (III) diacetate (PIDA) is reported. Six 3,5‐diamino‐4 ‐1,2,6‐thiadiazin‐4‐ones were oxidized to the corresponding sulfones (67–95 % yields) most efficiently using PIFA (3 equiv.). A 3,5‐diphenylthio analog...

A new imidazole-2-thione fused furazan biheterocyclic group was synthesized and its biological activity investigated. Nitrogen rich heterocycles, 1,2,5-oxadiazole (furazan) have been conveni ently fused. To accomplish this, we improved a strategy that silica gel supported solvent free micro wave dehydration of vicinal dioximes. The target "N,N’-diphenyl-4H-imidazo[4,5-c]furazan-5(6H) –thio ne" ...

A series of new clubbed aryl oxadiazole-1,2,4-triazine derivatives (6a-l) were designed and synthesized using appropriate chemical routes. The structures to have the required structural elements for any compounds be potential anticonvulsant. Preliminary screening anticonvulsant activity was performed maximal electroshock seizure (MES), subcutaneous pentylenetetrazole-induced (scPTZ) behavioral ...

Introduction: Oxidative stress and resulting lipid peroxidation are involved in numerous pathological conditions. For this reason, the role of antioxidants attracts attention radical-scavenging capacity many natural synthetic supplements drugs has been extensively evaluated. Material methods: In present study, seven N,N'-disubstituted benzimidazole-2-thiones with ester (1 - 4) hydrazide (5 7) s...