The broad capacity of pluripotent human embryonic stem cells (hESC) to grow and differentiate demands the development of rapid, scalable, and label-free methods to separate living cell populations for clinical and industrial applications. Here, we identify differences in cell stiffness, expressed as cell elastic modulus (CEM), for hESC versus mesenchymal progenitors, osteoblast-like derivatives...

Disrupted vegetation is often used as an indicator for landslide activity in forested regions. The extraction of irregular trees from airborne laser scanning data remains problematic because of low quality of observed data and paucity of field data validation. We obtained high density airborne LiDAR (HDAL) data with 180 points m -2 for characterizing tree growth anomalies caused by landslides. ...

Evaluating and optimizing e-government services is imperative for governments especially due to the capacity of e-services to transform public administrations and assist the interactions of governments with citizens, businesses and other government agencies. Existing widely applied evaluation approaches neglect to incorporate citizens’ satisfaction measures. Several citizen satisfaction models ...

Project results show that the international industrial networks in CEE are organized by MNCs and are limited in scope (mainly intra-firm). The weakest node for further industry upgrading via network alignment is a national network. There are big national differences in network alignment across CEECs. These differences reflect differences in the strategies of MNCs; the different roles of governm...

1 Introduction The current process of east-west European integration is a particularly striking example of the re-emergence of strong trade and, more generally, production linkages between two groups of economies which, albeit geographically close to each other, have had minimal trade and FDI links over a forty-year period. The rapid and deep liberalization of external relations after 1989 (acc...

This paper presents an approach to accelerate the simulation of shipboard power systems. A common issue in the ship research community is the simulation run time of large-scale shipboard power systems. A contributor to lengthy run times is that PC-based power system simulators do not exploit multicore technology, which stems from the fact that software trails advances in hardware. The Center fo...

Background: The Women’s Health Initiative (WHI) clinical trial of conjugated equine estrogens (CEEs), involving 10 739 postmenopausal women with hysterectomy, aged 50 to 79 years, was stopped early owing to lack of overall health benefit and increased risk of stroke. Because CEE is still prescribed for treatment of menopausal symptoms and prevention of osteoporosis, it is important to understan...

Metal-free transfer hydrogenation of polarized olefins (RR'C=CEE': R, R' = H or organyl, E, E' = CN or CO(2)Me) using amine borane adducts RR'NH-BH(3) (R = R' = H, AB; R = Me, R' = H, MAB; R = (t)Bu, R' = H, tBAB; R = R' = Me, DMAB) as hydrogen donors, were studied by means of in situ NMR spectroscopy. Deuterium kinetic isotope effects and the traced hydroboration intermediate revealed that the...

SUMMARY This paper explores growth and competitive advantage in CEE software firms; it looks at the role of strategic partnerships and industry (spillover) effects. The empirical analysis is based on survey data from 224 software firms from six CEE countries (Bulgaria, Czech R, Estonia, Serbia, Slovenia, Romania). The results of the descriptive analysis are interpreted from the perspective of t...

The effects of 1,3-bis(2-chloroethyl)-1-nitrosourea on the rejoining of X-ray-induced DNA strand breaks were examined in normal human fibroblasts (WI-38) and a simian virus 40-transformed derivative (VA-13) with the use of alkaline sucrose sedimentation. 1,3-Bis(2-chloroethyl)-1-nitrosourea was capable of partially inhibiting repair of X-ray-produced DNA strand breaks in both cell types when th...