We report the development of a low-cost chronic multi-channel microwire electrode array for recording multi-unit cortical responses in behaving rodents. The design was motivated by three issues. First, standard connector systems tended to disconnect from the head-stage during extended periods of behavior. Disconnections resulted in a loss of data and an interruption of the animals' behavior. Se...

OBJECTIVE We evaluated the efficacy of family-based, behavioral weight control in the management of severe pediatric obesity. METHODS Participants were 192 children 8.0 to 12.0 years of age (mean +/- SD: 10.2 +/- 1.2 years). The average BMI percentile for age and gender was 99.18 (SD: 0.72). Families were assigned randomly to the intervention or usual care. Assessments were conducted at basel...

Dietary weight loss regimens could be more effective by selectively targeting adipose while sparing lean mass (LM) if predictive information about individuals' lipid metabolic responses to an intervention were available. The objective of this study was to examine the relationships among changes in 4 anthropometric outcomes, weight, waist circumference (WC), percent body fat (BF), and percent LM...

BACKGROUND Many Americans are using alternative medical therapies as well as nutritional or dietary supplements that include vitamins, minerals, herbal products, tissue extracts, protein solutions, and other chemicals. Potential for both good and harm exists in taking many of these preparations. METHODS We surveyed 200 consecutive patients older than 18 years attending a family practice clini...

No other group is as disengaged from elections as youth. Voter turnout in the United States trails that of other industrialized societies, and is particularly anemic among youth between the ages of 18 and 24. The under-representation of youth voters has been observed ever since eighteen year olds were enfranchised in 1972 (for evidence, see Levine and Lopez, 2002; Bennett, 1997). In the 1976 el...

Bronchogenic cysts are congenital anomalies of the bronchial tree that are often asymptomatic at presentation in adults. Management of asymptomatic bronchogenic cyst in this population remains controversial. Eighteen patients with bronchogenic cysts were treated at our institution since 1975. At initial presentation, 10 patients (56 percent) were asymptomatic and 8 (44 percent) were symptomatic...

The mechanism by which clonidine suppresses renin secretion was investigated in pentobarbital-anesthetized dogs in which renal perfusion pressure was controlled by means of an aortic clamp. Clonidine (30 microgram/kg, iv) lowered mean arterial pressure (MAP) from 124 +/- 8 to 104 +/- 4 mm Hg (P less than 0.01) and reduced plasma renin activity (PRA) to 32 +/- 4 percent of the control value (P l...