Background: Infertile couples in the reproductive failure, after a year of sex without contraception is described and in 10 to 15% of couples can be seen, that the 1/3 because of the male, 1/3 female and the rest are a common cause. Factors involved in human infertility, the expression of microbial infection (25%), biological factors, environmental and genetic (50%) and unknown causes (25%) are...

Incubation of INT407 cells with various clinical isolates of Campylobacter jejuni resulted in secretion of interleukin-8 (IL-8) at levels ranging from 96 to 554 pg/ml at 24 h. The strains which produced the highest levels of IL-8 secretion were 81-176 and BT44. Induction of IL-8 secretion required live cells of 81-176 and was dependent on de novo protein synthesis. Site-specific mutants of 81-1...

Brucellosis is a major disease of domesticated and wild animals worldwide, and is also an important zoonosis. Of the domesticated species, cattle, sheep, pigs and goats are most commonly affected, and reproductive failure is the most common clinical manifestation. Infection in horses is uncommon, but is usually associated with infectious bursitis, arthritis or tenosynovitis. Less commonly, case...

Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 14, No. 9, September 2008 1485 Mayboun Heuangvongsy, Chanpheng Thammavong, Bouachanh Rasachack, Bounkong Syhavong, Nicholas J. White, Suriyasack Thongpaseuth, Anisone Changthongthip, Viengmone Davong, Olay Lattana, Manivanh Vongsouvath, Kai-amporn Keopaseuth, Sengmani Symanivong, Viengmala Sihalath, and Alatsany Chandara for participating in...

Introduction Ultra-orphan drugs are medicines used to treat exceptionally rare diseases that are chronically debilitating or life-threatening. Low patient numbers make it difficult for pharmaceutical companies to recoup research and development costs, and consequently these medicines are generally very expensive on a per patient basis. European Union (EU) regulations promote the development of ...