In the presence of covariate measurement error with the proportional hazards model, several functional modeling methods have been proposed. These include the conditional score estimator (Tsiatis and Davidian, 2001, Biometrika 88, 447-458), the parametric correction estimator (Nakamura, 1992, Biometrics 48, 829-838), and the nonparametric correction estimator (Huang and Wang, 2000, Journal of th...

Membrane proteins and membrane lipids are frequently organized in submicron-sized domains within cellular membranes. Factors thought to be responsible for domain formation include lipid–lipid interactions, lipid–protein interactions and protein–protein interactions. However, it is unclear whether the domain structure is regulated by other factors such as divalent cations. Here, we have examined...

Nausea and vomiting of pregnancy (NVP) affects approximately 80% of pregnant women. Its cause remains largely undetermined. The aim of this study was to assess the effect of fetal sex on tendency of NVP. A population-based study comparing all singleton pregnancies of patients carrying male and female fetuses was performed in Shahid Sadoughi hospital, Yazd, Iran from May 2010 to April 2011. Data...

A1 domain of tenascin-C 827 ABCB1 560 ABCG2 567 acne 411 acrylamide 1749 active drug combinations 1369 adenocarcinoma 217 adenovirus 1822 adjusted calcium 870 adjuvant chemoradiotherapy 1163 adjuvant chemotherapy 1788 adolescent cancer 1448 advanced solid tumours 993, 1554 age 112, 416, 970 aggressive fibromatosis 482 ago2 532 albumin 870 ALCAM 1048 alcohol consumption 127, 741, 747 ALKBH2 362 ...

OBJECTIVE Intraoperative blood loss in patients undergoing oncological spine surgery poses a major challenge for vulnerable patients. The goal of this study was to assess how the surgical procedure, tumor type, and anatomy, as well anesthesiological parameters, affect intraoperative use information generate short preoperative checklist surgeons anesthesiologists identify at risk increased loss....

Introduction To evaluate the effect of method induced abortion and other abortion-associated variables on incidence fear childbirth in subsequent pregnancy. Material methods This population-based register study cohort includes all nulliparous women with their first pregnancy ending an 2000-2015 live singleton delivery between 2000 2017 (n = 21 479). Data were derived from three national registe...

The gamma radiation in samples of a variety of natural tiling rocks (granites) imported in Cyprus for use in the building industry was measured, employing high-resolution gamma-ray spectroscopy. The rock samples were pulverised, sealed in 1-l plastic Marinelli beakers, and measured in the laboratory with an accumulating time between 10 and 14 h each. From the measured gamma-ray spectra, activit...

Based on individual patient data, we performed a quantitative overview of trials in hypertension to investigate to what extent lowering of systolic blood pressure (SBP) and diastolic blood pressure (DBP) contributed to cardiovascular prevention. We selected trials that tested active antihypertensive drugs against placebo or no treatment. Our analyses included 12,903 young (30 to 49 years of age...

BACKGROUND Radiographic manifestations of pulmonary tuberculosis (TB) in patients with diabetes mellitus (DM) have previously been reported, with inconsistent results. We conducted a study to investigate whether glycemic control has an impact on radiographic manifestations of pulmonary TB. METHODS Consecutive patients with culture-positive pulmonary TB who had DM in three tertiary care hospit...

AIMS Patients with diabetes are at excessive risk of mortality and cardiovascular morbidity. Previous studies suggest that aspirin may be less effective in diabetic patients. In this multi-centre, randomized, double blind trial picotamide, a dual inhibitor of thromboxane A2 synthase and receptor, was compared with aspirin for the prevention of mortality and major cardiovascular events in diabet...