BACKGROUND STAT is the backward position of cytokine and growth factor receptors in the nucleus, STAT dimers could bind to DNA and induce transcription of specific target genes. Several lines of evidence support the important roles of STAT, especially STAT5, in carcinogenesis. The overexpression of STAT 5 is related to the differentiation and apoptosis of tumor cells. However, the role of STAT5...

TrmB is an -glucoside-sensing transcriptional regulator controlling two operons encoding maltose/trehalose and maltodextrin ABC transporters ofPyrococcus furiosus. The crystal structure of an N-terminal truncated derivative of TrmB (amino acids 2–109 deleted; TrmB 2–109) was solved at 1.5 Å resolution. This protein has lost its DNA binding domain but has retained its sugar recognition site. The...

BACKGROUND The aim of this study was to determine the effect of commonly self-prescribed proton pump inhibitors (PPI) on the results of rapid urease test and histology for the diagnosis of H. pylori infection. METHODS One hundred-nine consecutive patients with dyspeptic symptoms attending the endoscopy suite were enrolled in this study. Antrum biopsy specimens were collected at endoscopy for ...

Report of a Case | Awoman in her 50s and her daughter, in her 30s, presented simultaneously with painful pustules on the palms (Figure, A) and a few on the soles. The eruption began 5 days after culture-proven group A streptococcal pharyngitis in thedaughter and tonsillitis in themother. Bothwere systemicallywell with no fever, arthropathy, ormucosal lesions. Both patients had already received ...

Participation of the intervascular transport system within the rice stem during cadmium (Cd) partitioning was investigated by characterizing (109)Cd behaviour in the shoot. In addition, (45)Ca, (32)P, and (35)S partitioning patterns were analysed for comparison with that of (109)Cd. Each tracer was applied to the seedling roots for 15 min, and the shoots were harvested either at 15 min (i.e. im...

Richard S. Gross (Jet Propulsion laboratory, California institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91 109; ph: 1-818-354-4010; fx: 1-818-393-6890; email: Richard [email protected]. gov) Yi Chao (Jet Propulsion Laboratory, California Institute of Teclmology, 4800 Oak Grove Drive, Pasadena, CA 91 109; ph: 1-818-354-8168; fx: 1-81 8-393-6720; email: [email protected]. gov) Steven L. ...