نتایج جستجو برای: 10 gene

تعداد نتایج: 2040721  

Journal: :Journal of immunology 2002
Zandong Yang Meng Chen Runpei Wu Lawrence B Fialkow Jonathan S Bromberg Marcia McDuffie Ali Naji Jerry L Nadler

Th1 cell activation and cytokine production shift the balance between Th1 and Th2, favoring the up-regulation of proinflammatory activity that leads to destruction of insulin-producing pancreatic beta cells in type 1 diabetes. Th2-type cytokines, such as IL-10, have immune regulatory function. Administration of IL-10, or IL-10 gene transfer, prevents autoimmune diabetes in nonobese diabetic (NO...

ژورنال: افق دانش 2020

Aims: Type 2 diabetes is a rising problem and a significant risk factor for small and large vessel disease. The present study aims to investigate the effect of a 6-week aerobic exercise program on High-mobility Group Box 1 (HMGB1) gene expression in aortic tissue of diabetic rats. Methods & Materials: In this experimental study, 40 male rats aged 8 weeks were randomly selected. Once familiariz...

Background: Unit of p65 is one of the subunits of NF-κB and its phosphorylation by stress oxidative causes activation of NF-κB. The aim of present study was to investigate the effects of adenosine injection after brain ischemia reperfusion injury on gene expression of NF-κB /p65 and Reactive Oxygen Species (ROS) in hippocampus tissue of male wistar rats. Methods: 40 male wistar rats were rando...

Journal: :Journal of medical genetics 2002
B Van Der Zwaag H T F M Verzijl D Beltran-Valero De Bernabe V L Schuster H Van Bokhoven H Kremer M Van Reen G H Wichers H G Brunner G W Padberg

B van der Zwaag, H T F M Verzijl, D Beltran-Valero de Bernabe, V L Schuster, H van Bokhoven, H Kremer, M van Reen, G H Wichers, H G Brunner, G W Padberg . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...

Journal: :Frontiers in Medicine 2023

EDITORIAL article Front. Med., 08 August 2023Sec. Gene and Cell Therapy Volume 10 - 2023 | https://doi.org/10.3389/fmed.2023.1225551

2010
Frances Shannon Guobing Chen Kristine Hardy Karen Bunting Stephen Daley Lina Ma

Background: DNA microarray is a useful technology that simultaneously assesses the expression of thousands of genes. It can be utilized for the detection of cancer types and cancer biomarkers. This study aimed to predict blood cancer using leukemia gene expression data and a robust ℓ2,p-norm sparsity-based gene selection method. Materials and Methods: In this descriptive study, the microarray ...

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