Elastase intratracheal instillation induces early emphysema in rodents. However, Syrian Golden hamsters develop more severe emphysema than Sprague-Dawley rats. We have reported species differences in oxidant/antioxidant balance modulating antiprotease function early after instillation. We now hypothesize that other components of the initial lung response to elastase might also be species-depend...

the importance of cats in the leptospira epidemiology is due to the possibility of transferring leptospirosis to wild and domesticated animals. the purpose of this survey was to determine the prevalence of leptospira infection in shorthair cats in different location of mashhad, iran. totally, 147 blood samples were taken from 42 (28.57%), 52 (35.37%) and 53 (36.05%) households, stray and cats w...

Cousinia papillosa (Asteraceae) from eastern Iran is described and illustrated as a new species. Differences between the new species and its closest relative, C. meshhedensis, are discussed. A map showing the distribution of the two species is given. The scanning electron micrography of the pollen grains shows obvious differences between the two species especially in the sculpturing of exine. T...

OBJECTIVES First, to highlight the major differences among mental health acts in different Canadian jurisdictions as they relate to involuntary admission criteria, treatment authorization, review and appeal procedures, and conditional leave and community treatment orders. Second, to analyze the impact of these differences on the care that individuals with mental illness receive. METHOD We exa...

Nucleocapsid (N) proteins from representative viruses of three genera within the Paramyxoviridae were expressed in insect cells using recombinant baculoviruses. RNA-containing structures, which appear morphologically identical to viral nucleocapsids, were isolated and subsequently imaged under a transmission electron microscope. Analysis of these images revealed marked differences in nucleocaps...

As the volume of content served by content distribution networks (CDNs) grows, these networks evolve to improve performance. Their performance is difficult to characterize because it depends on a number of factors. In this paper, we develop a methodology called DBit that can determine whether one CDN’s user-perceived performance is statistically different from another. We validate DBit and demo...

A typical use for RNA expression microarrays is comparing the measurement of gene expression of two groups. There has not been a study reproducing an entire experiment and modeling the distribution of reproducibility of fold differences. Our goal was to create a model of significance for fold differences, then maximize the number of ESTs above that threshold. Multiple strategies were tested to ...

Aromatase inhibitors are endocrine agents with a different mode of action than tamoxifen against breast tumors. In postmenopausal women, estrogen concentrations are maintained primarily via aromatase, a cytochrome P-450 enzyme that acts at the final step in the estrogen synthesis pathway. The first clinically available aromatase inhibitor, aminoglutethimide, was introduced for the second-line t...