To broaden the applicability of adoptive T-cell therapy for the treatment of hematologic malignancies, we aim to start a clinical trial using HA-1-TCR transferred virus-specific T cells. TCRs directed against the minor histocompatibility antigen (MiHA) HA-1 are good candidates for TCR gene transfer to treat hematologic malignancies because of the hematopoiesis-restricted expression and favorabl...

A field experiment was conducted to assess the effect of farmyard (cattle) manure (FYM) and inorganic nitrogen (N) phosphorus (P) fertilizers on growth and tuber yield of potato (Solanum tuberosum L.). The treatments consisted of factorial combination of 4 levels of FYM (0. 10, 20 and 30 t h-1) and three levels of inorganic NP fertilizers (0, 33.3%, 66.6% recommended rates) laid out in a Random...

The graft-versus-leukemia effect of allogeneic stem-cell transplantation is believed to be mediated by T-cell recognition of minor histocompatibility antigens on recipient cells. For minor histocompatibility antigens HA-1 and HA-2, normal cell expression is restricted to hemopoietic cells, and boosting the immune response to these antigens may potentiate graft-versus-leukemia effect without acc...

in order to evaluate the effects of ethephon and nitrogen fertilizer on sweet sorghum cv. sofra, an experiment was conducted as split plot on a randomized complete block design with three replications at agricultural research station of isfahan university (isfahan, iran). experiment was conducted with four nitrogen levels (0, 100, 200 and 300 kg urea ha-1 from urea with 0, 46, 92 and 138 kg nit...

The in vitro fate of the saturated hydrocarbon fraction (SF) of Arabian Light crude oil has been studied in PVC cores filled with a coastal marine sediment defaunated by sieving. Experiments were conducted in absence or presence of polychaetes Nereis diversicolor. The luminophore tracer technique was used to quantify the mixing of sediment by worms. Presence of crude oil reduced the building of...

Zeolite Phi is synthesized by two methods reported previously. Results from X-ray powder diffraction and scanning electron microscopy suggest that t h e materials are physical mixtures of chabazite and offretite; one sample has a small amount of phillipsite. The X-ray powder diffraction data from these samples, and those reported previously, are indexed and their unit-cell parameters compare we...

Minor histocompatibility Ags (mHags) are important targets of the graft-versus-leukemia effect after HLA-matched allogeneic stem cell transplantation. mHags are HLA-restricted polymorphic peptides expressed on normal and leukemia cells. Vaccination with hematopoiesis-restricted mHag peptides, such as HA-1, may boost the graft-versus-leukemia effect. However, some animal studies indicate that pe...

risk assessment of soil erosion, one of the most important land degradation problems worldwide, is very essential for land and water resources management, and development of soil conservation methods. in the present study, the temporal changes of soil erosion risk were assessed from 1987 to 2010, based on the revised universal soil loss equation (rusle) using remote sensing (rs) and geographic ...

The conservation technologies and traditional techniques were evaluated at Adaptive Research Farm Gujranwala Pakistan during Rabi 2007-2008 and 2008-2009. The sowing techniques evaluated were broadcasting (T-1), Rotary Tillage Drill (T-2), Zero Tillage Drill (T-3) and Rabi Drill (T-4). Rotary Tillage Drill showed significantly high germination count (220.50 m -2 ) followed by Rabi Drill (211.50...

The experiment was carried out to investigate the effect of nutrient combinations and spacing on growth performance mungbean (BARI mung 5) using split plot design. comprised 3 levels spacing; S1- 20 cm × 10 cm, S2- 30 S3- 45 15 cm; 6 fertilizers; F0- Control (without fertilizer), F1- Recommended dose NPK, F2- 5 t ha-1 cowdung, F3- cowdung + F4- 2.5 NPK F5- ha-1cowdung ½ NPK. Among different tre...