The human 25S U4/U6.U5 tri-snRNP is a major building block of the U2-type spliceosome and contains, in addition to the U4, U6, and U5 snRNAs, at least 30 distinct proteins. To learn more about the molecular architecture of the tri-snRNP, we have investigated interactions between tri-snRNP proteins using the yeast two-hybrid assay and in vitro binding assays, and, in addition, have identified di...

In the Tabas coal preparation plant (SE Iran), -50 + 6 mm raw coal was treated in a 700 mm two-stage two-density Tri-Flo dynamic dense medium separator. In order to study the circuit performance and to evaluate the separator efficiency, 32 mm cubic density tracers were used in the range of 1.28-2.1 g/cm3 and under different operational conditions. The performance of Tri-Flo was evaluated in a r...

We point out two simple but instructive possibilities to modify the tri-bimaximal neutrino mixing ansatz, such that leptonic CP violation can naturally be incorporated into the resultant scenarios of nearly tri-bimaximal flavor mixing. The consequences of two new ansätze on solar, atmospheric and reactor neutrino oscillations are analyzed. We also discuss an interesting approach to construct le...

BACKGROUND Adoption of transradial percutaneous coronary intervention (TRI) in the United States is low and may be related to challenges learning the technique. We examined the relationships between operator TRI volume and procedural metrics and outcomes. METHODS AND RESULTS We used CathPCI Registry data from July 2009 to December 2012 to identify new radial operators, defined by an exclusive...

In the structure of the title salt, C6H16N2 (2+)·2NO3 (-), the cations are connected to the anions through bifurcated N-H⋯(O,O) and weak C-H⋯O hydrogen bonds, generating corrugated layers parallel to the (100) plane. The organic cation is centrosymmetric and the diprotonated piperazine ring adopts a chair conformation, with the methyl groups occupying equatorial positions.

The title com pound, unreported as an insect pheromone com ponent, effectively attracted certain male Gelechiidae (genera Chionodes, M onochroa, Argolam protes) as a sin­ gle chemical. Trap captures with this chemical decreased on addition o f either (E)-3-dodecenyl acetate, (£)-3-tetradecenyl acetate or (Z )-3-tetradecen-l-ol, the sexual attractants of other, closely related species. Results o...

1. Sodium (N-acetyl-N-phenylhydroxylamine beta-d-glucosid)uronate was isolated from the urine of rabbits receiving N-acetyl-N-phenylhydroxylamine. 2. Its chemical structure was confirmed by the correspondence of the infrared spectrum of its tri-O-acetyl methyl ester derivative with the tri-O-acetyl methyl ester derivative of an authentic specimen prepared by the Koenigs-Knorr synthesis.

The role of electron microscopy in the assessment of dermatomyositis 1 2 Dr Hisham Alkhalidi 3 Assistant Professor and Consultant Pathologist Department of Pathology (32) College of 4 Medicine King Saud University P.O. Box 2925 Riyadh 11461 Saudi Arabia Telephone: 5 +966-533408611 Fax: +966-1-4672462 6 [email protected] 7 8 9 Abstract 10 11 Aim: To assess the importance of electron microscopy ...

The dinuclear barium-zinc complex, μ-chlorido-1:2κ(2) Cl:Cl-chlorido-2κCl-bis-(2-meth-oxy-ethanol-1κO)bis-(2-meth-oxy-ethanol-1κ(2) O,O')bis-(μ-tri-phenyl-acetato-1:2κ(2) O:O')bariumzinc, [BaZn(C20H15O2)2Cl2(C3H8O2)4], has been synthesized by the reaction of barium tri-phenyl-acetate, anhydrous zinc chloride and 2-meth-oxy-ethanol in the presence of toluene. The barium and zinc metal cations in...

PEGylated chlorin e(6) photosensitizers were synthesized with tri(ethylene glycol) attached at the ester bond(s) for a 1:1 conjugate at the 17(3)-position, a 2:1 conjugate at the 15(2)- and 17(3)-positions, and a 3:1 conjugate at the 13(1)-, 15(2)-, and 17(3)-positions. These chlorin sensitizers were studied for hydrolytic stability and solubility, as well as ovarian OVCAR-5 cancer cell uptake,...