The main objective of this paper is to add one more brick in building the CG model as a knowledge representation model autonomous from logic. The CG model is not only a graphical representation of logic, it is much more: it is a declarative model encoding knowledge in a mathematical theory, namely labelled graph theory, which has eecient computable forms, with a fundamental graph operation on t...

All known life requires phosphorus (P) in the form of inorganic phosphate (PO4 3x or Pi) and phosphate-containing organic molecules. Pi serves as the backbone of the nucleic acids that constitute genetic material and as the major repository of chemical energy for metabolism in polyphosphate bonds. Arsenic (As) lies directly below P on the periodic table and so the two elements share many chemic...

BACKGROUND Phosphohistidine phosphatase 1 (PHPT1), also named protein histidine phosphatase (PHP), is a eukaryotic enzyme dephosphorylating proteins and peptides that are phosphorylated on a histidine residue. A preliminary finding that histone H1, which lacks histidine, was phosphorylated by phosphoramidate and dephosphorylated by PHPT1 prompted the present investigation. METHODS Histone H1 ...

Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that indicates the possibility of viral migration to the human vestibular labyrinth. Distribution of HSV-1 DNA was determined in geniculate ganglia,...

The cysteinyl leukotrienes (cys-LTs) LTC(4), LTD(4), and LTE(4) are a class of peptide-conjugated lipids formed from arachidonic acid and released during activation of mast cells (MCs). We now report that human cord-blood-derived MCs (hMCs) express the CysLT1 receptor, which responds not only to inflammation-derived cys-LTs, but also to a pyrimidinergic ligand, UDP. hMCs express both CysLT1 pro...

In the following, RA refers to [MR95]. 1. JL also preserves angles. Show that the Johnson-Lindenstrauss lemma also (1±ε)-preserves angles among triples of points of P (you might need to increase the target dimension however by a constant factor). [Hint: For every angle, construct a equilateral triangle that its edges are being preserved by the projection (add the vertices of those triangles [co...

Extending axons are guided in part by diffusible chemoattractants that lure them to their targets and by diffusible chemorepellents that keep them away from nontarget regions. Floor plate cells at the ventral midline of the neural tube express a diffusible chemoattractant, netrin-1, that attracts a group of ventrally directed axons. Here we report that floor plate cells also have a long-range r...