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Measurement of the leptonic asymmetry in t[¯ over t] events produced in p[¯ over p] collisions at s = 1.96TeV. Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Meas...
The human leukocyte antigen (HLA) genes are candidate genetic susceptibility loci for childhood acute lymphoblastic leukemia (ALL). We examined the effect of HLA-DP genetic variation on risk and evaluated its potential interaction with 4 proxies for early immune modulation, including measures of infectious exposures in infancy (presence of older siblings, daycare attendance, ear infections) and...
The receptor tyrosine kinase (RTK) ROR1 is overexpressed and of importance for the survival of various malignancies, including lung adenocarcinoma, breast cancer and chronic lymphocytic leukemia (CLL). There is limited information however on ROR1 in melanoma. In the present study we analysed in seven melanoma cell lines ROR1 expression and phosphorylation as well as the effects of anti-ROR1 mon...
The present experiment was undertaken to validate a probiotic of canine origin for its potential use in dogs. A total of fifteen adult female Labrador dogs were allocated to three equal groups and fed a basal diet without probiotic (control) or with probiotic of either canine (Lactobacillus johnsonii CPN23; cPRO) or dairy (L. acidophilus NCDC 15; dPRO) origin for 9 weeks. The digestibility of m...
OBJECTIVES To explore the prognostic role of CK19 expression in squamous cell carcinomas within a well-defined cohort of oral tongue cancer patients. METHODS In our retrospective study, we investigated 129 patients with tongue cancer that had suitable material for inclusion in a tissue microarray (TMA). Where possible, samples were taken from central and peripheral regions of the tumor to gen...
OBJECTIVE This secondary data analysis explored factors influencing job satisfaction in a sample of nursing assistants employed in Maryland skilled nursing facilities. BACKGROUND Multiple factors have been shown to affect job satisfaction and turnover in nursing assistants (NAs), but the problem of turnover persists in skilled nursing facility environments affecting quality of care. METHODS...
BACKGROUND AND OBJECTIVES Gaps exist in inpatient asthma care. Our aims were to assess the impact of an evidence-based care process model (EB-CPM) 5 years after implementation at Primary Children's Hospital (PCH), a tertiary care facility, and after its dissemination to 7 community hospitals. METHODS Participants included asthmatics 2 to 17 years admitted at 8 hospitals between 2003 and 2013....
We have discovered an isotopically highly anomalous MgSiO3 grain in the ungrouped carbonaceous chondrite Acfer 094 with a perovskite-like crystal structure resembling the dominant high-pressure mineral of the Earth’s lower mantle. Oxygen isotopic ratios of the silicate grain are O/ O p (4.91 0.36) # 10 (12 times the 3 solar value) and O/O p (1.36 0.19) # 10 (0.4 times the solar value). This sig...
Let p be a prime congruent to 1 modulo 4, and let t, u be rational integers such that (t + u √ p )/2 is the fundamental unit of the real quadratic field Q(√p ). The Ankeny-Artin-Chowla conjecture (AAC conjecture) asserts that p will not divide u. This is equivalent to the assertion that p will not divide B(p−1)/2, where Bn denotes the nth Bernoulli number. Although first published in 1952, this...
It is well known that BRCA1 and BRCA2 play a central role in DNA repair, but the relationship between BRCA1 and BRCA2 mRNA expression and response to neoadjuvant chemotherapy in sporadic breast cancer patients has not been well established. Here, we investigate the association between BRCA1 or BRCA2 mRNA expression levels and pathological response in 674 BRCA1/2 mutation-negative breast cancer ...
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