Bladder cancer is the 9th most common cancer and is responsible for malignancy related death all on the world. Folate and folate related enzyme polymorphisms related to the cancer risk. The methylene tethrahydrofolate reductase (MTHFR) enzyme is folate related and association of bladder cancer and MTHFR gene. Our purpose was to assess the prevalence of MTHFR gene 677 CT and 1298 AC polymorphism...

A new group of 5,5-diarylhydantoin derivatives bearing a methylsulfonyl COX-2 pharmacophore at the para position of the C-5 phenyl ring were designed and synthesized as selective COX-2 inhibitors. In vitro COX-1/COX-2 inhibition structure-activity relationships identified 5-[4-(methylsulfonyl)phenyl]-5-phenyl-hydantoin (4) as a highly potent and selective COX-2 inhibitor (COX-2 IC(50) = 0.077 μ...

INTRODUCTION: REFRAMING THE ISSUE OF RACE AND IMPRISONMENT .............. 1272 A. The Distinctive Features of African American Mass Incarceration .......... 1274 1. Total numbers incarcerated. . . . . . . . . . . .. .. . . . . . . . . .. . . . . . ...... .... . . . . . . .. ... . . .. . . . .......... 1274 2. Rate of incarceration . . ... ......... . . . . . ..... . . ............. . . ...... ....

موضوع مقاله حاضر، پژوهشی درباره انتساب آرامگاهی برجی در شهر آمل به حسن بن علی الطروش الحسینی ملقب به ناصر الحق(230ـ 304 ق) از امامان و فرمانروایان زیدی سده 4 ق مازندران و دلایل این اشتهار است. نگارنده کوشیده است با تکیه بر مآخذ تاریخ زیدیه، مراجع رجال و تواریخ محلی شرحی از زندگانی ناصرالحق ارائه دهد. و در پی آن ضمن بیان تاریخچه ساخت و بازسازی کامل ساختمان بقعه در سده 9 ق، از ویژگیهای معماری آن ...

389 Harald Baumeister Engelbergerstrasse 41 DE–79085 Freiburg (Germany) Tel. +49 761 203 3044, Fax +49 761 203 3040 E-Mail baumeister @ psychologie.uni-freiburg.de 3 Parker G: Beyond major depression. Psychol Med 2005; 35: 467–474. 4 Parker G, Roy K, Mitchell P, Wilhelm K, Malhi G, Hadzi-Pavlovic D: Atypical depression: a reappraisal. Am J Psychiatry 2002; 159: 1470– 1479. 5 Leventhal AM, Reh...

A new protocol similar to EPA method TO-14A was established to quantify and report variations in greenhouse gas (GHG) emissions from different ground level area sources (GLAS) in a free-stall dairy in central Texas. The objective of the study was to estimate and compare methane (CH4), carbon dioxide (CO2), and nitrous oxide (N2O) emission factors (EFs) from different GLAS using this new protoco...

We investigated the role of glutathione S-transferase (GST) enzymes (M1, T1), methylenetetrahydrofolate (MTHFR) 677 and 1298, and the NAD(P)H:quinone oxidoreductase (NQO1) polymorphisms in a population-based bladder cancer case-control study in Argentina. Buccal cell DNA was obtained from 106 cases and 109 controls. The strongest evidence was for an interaction between NQO1 genotype and smoking...

Background and Purpose—Statins reduce the risk of stroke recurrence, but the benefits of statins in improving outcome of acute stroke patients have not been well explored. Methods—We assessed potential effects of statins initiated before or within 4 weeks of stroke on 90-day outcome. Favorable outcomes were National Institutes of Health Stroke Scale (NIHSS) score 2 at 12 weeks and modified Rank...

Several general constraints are suggested to analyze the pionic valence-state wave function. It is found that the present model wave functions used in lightcone formalism of perturbative quantum chromodynamics have failed these requirements to fit the pionic formfactor data and the reasonable valence-state structure function which does not exceed the pionic structure function data for x → 1 sim...