نتایج جستجو برای: گلوتامیک اسید دکربوکسیلاز gad

تعداد نتایج: 24136  

Journal: :Behaviour research and therapy 2005
Douglas S Mennin Richard G Heimberg Cynthia L Turk David M Fresco

Three studies provide preliminary support for an emotion dysregulation model of generalized anxiety disorder (GAD). In study 1, students with GAD reported heightened intensity of emotions, poorer understanding of emotions, greater negative reactivity to emotional experience, and less ability to self-soothe after negative emotions than controls. A composite emotion regulation score significantly...

Journal: :Asian journal of psychiatry 2014
K G Vijay Ajit Avasthi Sandeep Grover

OBJECTIVE To study the phenomenon of worry and functional somatic symptoms in Generalized Anxiety Disorder (GAD). METHOD 40 subjects with the diagnosis of GAD were assessed by using Penn State Worry Questionnaire (PSWQ) and Bradford Somatic Inventory (BSI). Severity of GAD was rated on Generalized Anxiety Disorder -7 (GAD-7) scale. RESULTS The mean total score on PSWQ was 59.62. All patient...

Journal: :Journal of behavior therapy and experimental psychiatry 1998
L Ben-Noun

The purpose of this study was to investigate the relation between persistent prolonged dysfunction in parents and the development of Generalized Anxiety disorder (GAD). Initially, 940 adult subjects from a general practice were studied. Thirty-two parents aged 24 to 61 yr diagnosed with GAD served as the experimental group, while 117 healthy normal parents aged 24-66 yr made up the control grou...

2009
Ouria Dkhissi Jean-François Julien Jeanine Nguyen-Legros Claudine Versaux-Botteri

The development of synthetic enzymes in the GABAergic system (GAD and GAD ) of the rat retina was analyzed from birth to the 67 65 4th postnatal week by the reverse transcriptase polymerase chain reaction (RT–PCR) and by immunohistochemistry. As previously observed for GABA, immunoreactive GAD profiles are seen clearly in the inner retinal layers at birth. At the end of the 1st week of 67 postn...

Journal: :Clinical and experimental immunology 2013
M Chéramy C S Hampe J Ludvigsson R Casas

Previous studies have indicated phenotypical differences in glutamic acid decarboxylase 65 autoantibodies (GADA) found in type 1 diabetes (T1D) patients, individuals at risk of developing T1D and stiff-person syndrome (SPS) patients. In a Phase II trial using aluminium-formulated GAD(65) (GAD-alum) as an immunomodulator in T1D, several patients responded with high GADA titres after treatment, ...

Journal: :Psychological medicine 2009
S Lee A Tsang A M Ruscio J M Haro D J Stein J Alonso M C Angermeyer E J Bromet K Demyttenaere G de Girolamo R de Graaf O Gureje N Iwata E G Karam J-P Lepine D Levinson M E Medina-Mora M A Oakley Browne J Posada-Villa R C Kessler

BACKGROUND A number of western studies have suggested that the 6-month duration requirement of generalized anxiety disorder (GAD) does not represent a critical threshold in terms of onset, course, or risk factors of the disorder. No study has examined the consequences of modifying the duration requirement across a wide range of correlates in both developed and developing countries. METHOD Pop...

Journal: :Biological psychiatry 2008
Paul J Whalen Tom Johnstone Leah H Somerville Jack B Nitschke Sara Polis Andrew L Alexander Richard J Davidson Ned H Kalin

BACKGROUND Functional magnetic resonance imaging (fMRI) holds promise as a noninvasive means of identifying neural responses that can be used to predict treatment response before beginning a drug trial. Imaging paradigms employing facial expressions as presented stimuli have been shown to activate the amygdala and anterior cingulate cortex (ACC). Here, we sought to determine whether pretreatmen...

2010
TG Dinan

Generalised anxiety disorder (GAD) is defined as excessive and uncontrollable worry and anxiety about everyday life situations. It is a chronic disorder, and is associated with substantial somatisation, high rates of comorbid depression and other anxiety disorders, and significant disability. The evidence base for pharmacotherapy and psychotherapy has continued to grow, and a wide range of drug...

Journal: :JAMA 2014
Nathaniel R Herr John W Williams Sophiya Benjamin Jennifer McDuffie

IMPORTANCE In primary care settings, generalized anxiety disorder (GAD) and panic disorder are common but underrecognized illnesses. Identifying accurate and feasible screening instruments for GAD and panic disorder has the potential to improve detection and facilitate treatment. OBJECTIVE To systematically review the accuracy of self-report screening instruments in diagnosing GAD and panic d...

ژورنال: :مجله تحقیقات دامپزشکی (journal of veterinary research) 2009
بهار نیری فسایی تقی زهرایی صالحی حسن تاجبخش

ژن aroa یکی از ژن های مهم برای تولید اسید آمینه های آروماتیک می باشد و برای حیات باکتری بسیار ضروری است. نشان داده شده است، که توالی ژنی aroa در باکتری ها متفاوت است، بنابر این هدف این مطالعه تعیین توالی نوکلئوتیدی ژن aroa در سویه اشریشیا کلی بومی 80: k78o برای مشخص کردن تفاوت ها بین این سویه و سویه های موجود در بانک ژنی اشریشیا کلی 80: k78o بود. برای ازدیاد ژن aroa در سویه بومی از واکنش زنجیره...

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