The major goal of this study was to create a continuous time Markov chain (CTMC) models of voltage gating of gap junction (GJ) channels formed of connexin protein. This goal was achieved by using the Piece Linear Aggregate (PLA) formalism to describe the function of GJs and transforming PLA into Markov process. Infinitesimal generator of CTMC was used to automate construction of Markov chain mo...

Papillary thyroid carcinoma (PTC) is the most common malignant tumour of the thyroid. The effect of the concurrent presence of Hashimoto's thyroiditis (HT) and PTC is still under debate. The aim of this study is to investigate the influence of coexistent HT on prognostic outcomes and the association of coexistent HT with clinicopathological features. The demographic and clinicopathological data...

This study deals with the problem of establishing the network of emergency service units. The goal of the basic problem proposed in the literature is to locate certain number of units at given discrete points of the region and to allocate cities to established units, in order to balance the load of established emergency units. Having in mind that emergency units work in shifts, we extend the ba...

BACKGROUND To assess the extent of gastric intestinal metaplasia (IM) in gastrectomy specimens in populations of the Pacific basin having different incidence of gastric carcinoma. MATERIALS AND METHODS One thousand three hundred and nine-two gastrectomies were investigated: 1088 had a gastric carcinoma and 304 miscellaneous gastric diseases. Twenty-one thousand three hundred and fourteen hist...

Speech recognition is one of the fundamental requirements for fully autonomous robotic systems nowadays. The objective of the presented work is to offer a smartphone based speech recognition system for ROS (Robot Operating System) based autonomous robotic systems. The proposed recognition process consists of three steps, namely acquisition, preprocessing, and result extraction. In the contribut...

This paper presents a new automatic 3D mesh-based centerline extraction (3D-MCE) algorithm, which allows an accurate extraction of 3D centerline from a tubular geometry form, without manned intervention. The 3DMCE does not require any input parameters and works on polygon mesh vertices producing a thin, connected and centered centerline, without needing pre or post-processing stages. In order t...