This placebo-controlled, double-blind crossover study assessed whether exclusive activation of peripheral opioid receptors results in significant pain reduction. To achieve opioid activity restricted to the periphery, we used a short-term (2 h) low dose infusion of morphine-6-beta-glucuronide (M6G) because M6G does not pass the blood-brain barrier during this time in amounts sufficient to induc...

Introduction: Athletics training and competition is associated with increased oxidative stress inflammation, especially at moderate altitude. This results from an formation of reactive oxygen species due to metabolic activity working cells tissues as well decreased pressure. The can cause inflammation delayed onset muscle soreness (DOMS), which be a serious problem for athletes competing high c...

BACKGROUND In relation to Myofascial Triggerpoints (MFTrPs) of the upper Trapezius, this study explored muscle contractility characteristics, the occurrence of post-intervention muscle soreness and the effect of dry needling on muscle contractile characteristics and clinical outcomes. METHODS Seventy-seven female office workers (25-46yrs) with and without neck/shoulder pain were observed with...

BACKGROUND Muscle soreness and decreased performance often follow a bout of high-intensity exercise. By reducing these effects, an athlete can train more frequently and increase long-term performance. The purpose of this study is to examine whether a high-potency, black tea extract (BTE) alters the delayed onset muscle soreness (DOMS), oxidative stress, inflammation, and cortisol (CORT) respons...

Intermittent pneumatic compression (IPC) technolog ies are widely used in clinical populations to aid the reduction of limb oedema and for the prophylaxis of deep vein thromboses (DVT). IPC application within athletic populat ions is not however widespread. The main mechanism for the effectiveness of IPC is that it augments venous and arterial blood flow via the periodic inflation of external c...