Introduction. Innovative technologies, new approaches to the creation of medicines, a combination classic technological methods with latest trends makes pharmaceutical production direction positive dynamics development. But along emergence synthetic drugs, as well biotech products, use herbal raw materials for medicines remains relevant. Phytopreparations have number undeniable advantages over ...

Six new sesquiterpene coumarin derivatives, fukanefuromarin H-M (1-6), were isolated from an 80% aqueous methanol extract of the roots of Ferula fukanensis. The structures were elucidated on the basis of spectroscopic evidence, particularly heteronuclear multiple-bond connectivity (HMBC) and high-resolution MS. The sesquiterpene coumarin derivatives inhibited nitric oxide (NO) and inducible NO ...

Dormancy breaking and germination requirements were investigated in seeds of Ferula ovina and Ferula gummosa. Seeds of rather species were collected from north and eastern-north rangelands of Iran. Seeds of each of the species were subjected to different treatments including various levels of GA3, chilling and combination of GA3 and chilling (GA-chilling). In contrast to treated seeds, non-trea...

medical plants are adapted to different kinds of dormancy to survive in the worst situations. regarding to ecological viewpoint, this kind of adaptation is very important in respect to restriction of genetic draft and decrease of genetic resource of medicinal plants. this leads to plant survival even after prolonged drought. since some of them are endangered species and in the other hand increa...

Ferula communis L., subsp. communis, namely giant fennel, has extensively been used in traditional medicine for a wide range of ailments. Fresh plant materials, crude extracts and isolated components of F. communis showed a wide spectrum of in vitro and in vivo pharmacological properties including antidiabetic, antimicrobial, antiproliferative, and cytotoxic activities. The present paper, revie...