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100 www.thelancet.com Vol 365 January 8, 2005 to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation. J Clin Invest 1999; 103: 175–83. 5 Randolph DA, Carruthers CJ, Szabo SJ, Murphy KM, Chaplin DD. Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma. J Immunol 1999; 162: 2375–83. 6 Jonule...

5. Hartog, M., Gaafar, M. A., Fraser, R. Lancet, 1964, ii, 376. 6. Hunter, W. M., Willoughby, J. M. T., Strong, J. A. J. Endocr. 1968, 40, 297. 7. Cook, G. C. Metabolism, 1968, 17, 1073. 8. Luft, R. New Engl. J. Med. 1968, 279, 1086. 9. Luft, R., Cerasi, E. Acta endocr., Copenh. 1967, suppl. no. 124, p. 9. 10. Mintz, D. H., Finster, J. L., Taylor, A. L., Fefer, A. Am. J. Med. 1968, 45, 187. 11....

METHODS: This is a retrospective study of 732 patients with CMLBP who were treated between 1997 and 2007. All patients had received injections of methylprednisolone and bupivacaine into the facet joints of L3-4, L4-5, and L5-S1. None had tumor, infection, or major trauma causing fracture of the spine, disruption of the major ligaments of the lumbosacral spine, or cauda equina syndrome. Patients...

Biomedical sciences have made major advances in understanding how tissues repair, and the signalling mechanisms required to achieve this goal are progressively being dissected. Advances in the understanding of tissue repair mechanisms and the pivotal role of growth factors have stimulated the use of platelet-rich therapies by orthopaedic surgeons and sports physicians, mainly with the aim of st...

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439 1. Experiments with Animals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442 2. Studies with Humans . . . . . . . . . . . . . . . . . . . . . . . . . . ...

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313 1. The Placebo Effect in Sport . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 314 2. Findings of Intervention Studies . . . . . . . . . . . . . . . . . . . ...

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 390 1. Physiological Aspects of Exercise . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 391 1.1 Effects of Exercise on the Motor Unit . . . . . . . . . . . . . . . . . . ...

Prostate cancer is a major hormone-dependent tumor affecting men, and is often treated by hormone therapy at the primary stages. Despite its initial efficiency, the disease eventually acquires resistance, resulting in the recurrence of castration-resistant prostate cancer. Recent studies suggest that dysregulation of microRNA (miRNA) function is one of the mechanisms underlying hormone therapy ...

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 894 1. About Core Stability . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 895 1.1 The Core . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...