نتایج جستجو برای: ژن های inos و ifnγ

تعداد نتایج: 784919  

2011

In this work we study the effect of some electrical prosperities on synthetic rubber reinforced with carbon black diluted in heptanes with concentrations from 0.2% gm/mole to 2.0% gm/ mole in temperatures range (100, 150, 200, 250, 300) C associated with amount weight of black carbon 5wt% added to the diluted rubber. The results of electrical properties measurement of Buna rubber reinforced wit...

Journal: :Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2012
Mitsuru Ando Yuki Takahashi Makiya Nishikawa Yoshinobu Takakura

Type II interferon (IFNγ) is a representative Th1 cytokine and it possesses a variety of functions, including immune regulation, antiviral and antitumor activity. Because of its multifunctional nature, IFNγ is expected to be applied to the treatment of autoimmune diseases, cancer and viral infection. Although IFNγ has therapeutic potential for such diseases, the clinical use of IFNγ has been li...

2016
Renee L Greer Xiaoxi Dong Ana Carolina F Moraes Ryszard A Zielke Gabriel R Fernandes Ekaterina Peremyslova Stephany Vasquez-Perez Alexi A Schoenborn Everton P Gomes Alexandre C Pereira Sandra R G Ferreira Michael Yao Ivan J Fuss Warren Strober Aleksandra E Sikora Gregory A Taylor Ajay S Gulati Andrey Morgun Natalia Shulzhenko

Cross-talk between the gut microbiota and the host immune system regulates host metabolism, and its dysregulation can cause metabolic disease. Here, we show that the gut microbe Akkermansia muciniphila can mediate negative effects of IFNγ on glucose tolerance. In IFNγ-deficient mice, A. muciniphila is significantly increased and restoration of IFNγ levels reduces A. muciniphila abundance. We fu...

2008
Gustavo Duque Dao Chao Huang Michael Macoritto Daniel Rivas Xian Fang Yang Louis Georges Ste-Marie Richard Kremer

Interferon gamma (IFNγ) is a strong inhibitor of osteoclast differentiation and activity. However, its role in osteoblastogenesis has not been carefully examined. Using microarray expression analysis, we found that several IFNγ inducible genes were upregulated during early phases of osteoblast differentiation of human mesenchymal stem cells (hMSC). We therefore hypothesized that IFNγ may play a...

Journal: :Discovery immunology 2023

Abstract Interferon gamma (IFNγ) is a potent antiviral cytokine that can be produced by many innate and adaptive immune cells during infection. Currently, our understanding of which produce IFNγ where they are located at different stages an infection limited. We have used reporter mice to investigate in vivo expression Ifnγ mRNA the lung secondary lymphoid organs following influenza A virus (IA...

2012
Stephanie P. Jehl Catarina V. Nogueira Xuqing Zhang Michael N. Starnbach

The activation of host cells by interferon gamma (IFNγ) is essential for inhibiting the intracellular replication of most microbial pathogens. Although significant advances have been made in identifying IFNγ-dependent host factors that suppress intracellular bacteria, little is known about how IFNγ enables cells to recognize, or restrict, the growth of pathogens that replicate in the host cytop...

Journal: : 2022

هدف: کبد از حساس‌ترین بافت‌های هدف فشار اکسایشی ناشی تمرین می‌باشد و آمینوترانسفراز‌های کبدی، شاخص‌های حساسی برای تعیین آسیب دیدگی سلول‌های کبدی هستند. پژوهش حاضر با مقایسه تأثیر هشت هفته TRX مقاومتی سنتی بر برخی آنزیم‌های (آسپارتات آمینو ترانسفراز آلانین ترانسفراز) در زنان غیرفعال انجام گرفت.روش ­ها: این که به روش نیمه تجربی شد، 28 دختر میانگین سن41/1±07/21 سال شاخص توده بدن 25/4±52/22 کیلوگرم...

ژورنال: :المپیک مدرن 2013
زهرا جلالی ولی اله دبیدی روشن جواد اشرفی

برای مطالعة اثر تعاملی تمرینات استقامتی و مکمل آنتی اکسیدانت گیاهی بر شاخص های التهابی شامل ملکولو ضدالتهابی از قبیل مهارکنندة (hs-crp) و پروتئین واکنشی با حساسیت بالا (vcam- چسبان عروقی ( 148 سر ،(inos) در پرفشار خونی ناشی از مهارکنندة سنتتاز اکسید نیتریک (ace-i) آنزیم مبدل آنژیوتانسین. 4. باریجه، 5. تمرین استقامتی، 6 ،inos . موش به طور تصادفی به شش گروه تقسیم شدند: 1. پایه، 2. شم، 3inos تمرین...

Journal: :journal of sciences islamic republic of iran 0

inducible nitric oxide synthase (inos) gene expresses a calcium calmudolin-independent enzyme which can catalyse no production from l-arginine. the induction of inos activity has been demonstrated in a wide variety of cell types under stimulation with cytokines and lipopoly saccharide (lps). previous studies indicated that all nitric oxide synthases (nos) activated in human umbilical vein endot...

2016
Apurva Kulkarni Priya Ganesan Lauren A. O’Donnell

Interferon-gamma (IFNγ), a pleiotropic cytokine, is expressed in diverse neurodegenerative and neuroinflammatory conditions. Its protective mechanisms are well documented during viral infections in the brain, where IFNγ mediates non-cytolytic viral control in infected neurons. However, IFNγ also plays both protective and pathological roles in other central nervous system (CNS) diseases. Of the ...

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