نتایج جستجو برای: هپاتوسلولار کارسینوما hcc
تعداد نتایج: 14492 فیلتر نتایج به سال:
آملوبلاستیک کارسینوما، یک تومور بسیار نادر و بدخیم است که بیشتر در استخوان فک پایین ایجاد می شود و گروه سنی گسترده ای را درگیر می کند؛ گرایش به جنس خاصی ندارد؛ نمای میکروسکوپی اختصاصی خود را دارد و درمان جراحی تهاجمی تری را نسبت به آملوبلاستوما می طلبد. تعداد موارد گزارش شده از این بیماری، تاکنون اندک بوده و تشخیص آن بر مبنای یافته های میکروسکوپی، بسیار مشکل است؛ زیرا در تشخیص افتراقی با آملوبل...
N-myc downstream regulated gene 1 (NDRG1)/Cap43 is a 43 kDa protein that is widely distributed in the body. Its expression is regulated by nickel, cobalt, hypoxic condition and others; it is reported to be weaker in tumors than normal tissues; and NDRG1/Cap43 is considered to act suppressively to tumor metastasis. This current study immunohistochemically examined NDRG1/Cap43 expression in hepat...
BACKGROUND The value of hepatic resection (HR) for huge hepatocellular carcinomas (HCC) (≥ 10 cm in diameter) remains controversial. The aim of this study is to evaluate the efficacy of hepatic resection (HR) for patients with huge HCC. METHODS A total of 739 patients with huge HCC (≥ 10 cm in diameter) (huge HCC group, n = 244) or small HCC (< 10 cm in diameter) (small HCC group, n = 495) wh...
Abstract Multicentric fibrolamellar hepatocellular carcinoma has not been reported yet in the world as of our knowledge. A Medline search for term “multicentric HCC” did return any results. To knowledge, this is first case report multi-centric (HCC). We present a 22-year-old male patient who had complaints epigastric pain 1 month. His general physical examinations were normal. Computed tomograp...
Nonalcoholic fatty liver disease (NAFLD) is a spectrum that spans simple steatosis, fibrosis, and ultimately cirrhosis, leading cause of chronic globally. The severe variant NAFLD, non-alcoholic steatohepatitis (NASH), characterized by triglyceride accumulation within hepatocytes the subsequent inflammatory pathway activation, progressing to cirrhosis in 10%-20% patients. NASH known major risk ...
There is a rising incidence of non-alcoholic fatty liver disease (NAFLD) as well as of the frequency of Hepato-Cellular Carcinoma (HCC) associated with NAFLD. To seek for putative metabolic pathways specific of the NAFLD etiology, we performed comparative metabolomics between HCC associated with NAFLD and HCC associated with cirrhosis. The study included 28 pairs of HCC tissue versus distant No...
The OncoDB.HCC (http://oncodb.hcc.ibms.sinica.edu.tw) is based on physical maps of rodent and human genomes containing quantitative trait loci of rodent HCC models and various human HCC somatic aberrations including chromosomal data from loss of heterozygosity and comparative genome hybridization analyses, altered expression of genes from microarray and proteomic studies, and finally experiment...
Hepatocellular carcinoma (HCC) is the 6th most common cancer worldwide. Imaging plays a critical role in HCC screening and diagnosis. Initial screening of patients at risk for HCC is performed with ultrasound. Confirmation of HCC can then be obtained by Computed Tomography (CT) or Magnetic Resonance Imaging (MRI), due to the relatively high specificity of both techniques. This article will focu...
BACKGROUND Genetic polymorphisms of pri-miR-34b/c and pre-miR-196a2 have been reported to be associated with the susceptibility to cancers. However, the effect of these polymorphisms and their interactions with hepatitis B virus (HBV) mutations on the development of hepatocellular carcinoma (HCC) remains largely unknown. We hypothesized that these polymorphisms might interact with the HBV mutat...
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