The donor-acceptor semiconducting polymers (SPs) have robust absorbance in near-infrared (NIR) region, great photostability, high photothermal conversion efficiency, and good biocompatibility. Thus, the SPs exhibit great potentials for photothermal therapy (PTT) and photoacoustic imaging (PAI). However, poor understanding of the underlying mechanisms and the correlation between the SP polymer c...

STUDY OBJECTIVES Obstructive sleep apnea-hypopnea (OAH) diagnosis in children is based on the quantification of flow and respiratory effort (RE). Pulse transit time (PTT) is one validated tool to recognize RE. Pattern analysis of mandibular movements (MM) might be an alternative method to detect RE. We compared several patterns of MM to concomittant changes in PTT during OAH in children with ad...

Multifunctional nanoplatforms with integrated diagnostic and therapeutic functions have attracted tremendous attention. Especially, the second near-infrared (NIR-II) light response-based nanoplatforms hold great potential in cancer theranostic applications, which is because the NIR-II window provides larger tissue penetration depth and higher maximum permissible exposure (MPE) than that of the ...

INTRODUCTION Acute traumatic coagulopathy has been associated with shock and tissue injury, and may be mediated via activation of the protein C pathway. Patients with acute traumatic coagulopathy have prolonged PT and PTT, and decreased activity of factors V and VIII; they are also hypocoagulable by thromboelastometry (ROTEM) and other viscoelastic assays. To test the etiology of this phenomeno...

an attempt is made for the first time to solve the quadratic and cubic model of magneto hydrodynamic poiseuille flow of phan-thein-tanner (ptt). series solution of magneto hydrodynamic (mhd) flow is developed by using homotopy perturbation method (hpm). results are presented graphically and the effects of non-dimensional parameters on the flow field are analyzed. the results obtained reveals ma...

BACKGROUND In the photodynamic therapy (PDT), the photosensitizer absorbs light and transfers the energy of the excited state to the oxygen in the cell environment producing reactive oxygen species (ROS), that in its turn, may cause cell damage. In the photothermal therapy (PTT), light also is responsible for activating the photothermal agent, which converts the absorbed energy in heat. Graphen...

Abstract Background Photothermal therapy (PTT), involving application of localized hyperthermia to kill cancer cells, has attracted wide attention in therapy. The production reactive oxygen species (ROS) during PTT may cause irreversible damage healthy tissues around the tumor. Simultaneously, can stimulate inflammatory response, thus promoting tumor recurrence and metastasis. Therefore, it is ...

Nanohybrids using biocompatible and biodegradable materials are explored for their photothermal mediated theranostic applications. These hybrids so chosen that they biodegradable. Gold-based different nanosystems have NIR absorption which is highly favored PTT, but limited by toxicity, stability, clearance. To overcome these challenges, we demonstrated thermosensitive liposome-gold hybrid nanos...