نتایج جستجو برای: مدل sma

تعداد نتایج: 138859  

2013
Ignacio Obeso Noemí Robles Elena M. Marrón Diego Redolar-Ripoll

The pre-supplementary motor area (pre-SMA) is considered to be a key node in the cognitive control of actions that require rapid updating, inhibition, or switching, as well as working memory. It is now recognized that the pre-SMA is part of a "cognitive control" network involving the inferior frontal gyrus (IFG) and subcortical regions, such as the striatum and subthalamic nucleus. However, two...

Journal: :Investigative ophthalmology & visual science 1995
D Kurosaka K Kato T Nagamoto K Negishi

PURPOSE To determine whether basic fibroblast growth factor (bFGF) and transforming growth factor-beta 2 (TGF-beta 2) influence the contractile activity and the expression of alpha-smooth muscle actin (alpha-SMA) in bovine lens epithelial cells (LECs). To examine whether modulation of contractile activity by these growth factors depends on changes of alpha-SMA expression. METHODS Bovine LECs ...

2016
Zhidai Liu Penghui Zhang Xiaoyan He Shan Liu Shi Tang Rong Zhang Xinbin Wang Junjie Tan Bin Peng Li Jiang Siqi Hong Lin Zou

BACKGROUND Spinal muscular atrophy (SMA) is the most common autosomal recessive disease in children, and the diagnosis is complicated and difficult, especially at early stage. Early diagnosis of SMA is able to improve the outcome of SMA patients. In our study, Real-time PCR was developed to measure the gene mutation or deletion of key genes for SMA and to further analyse genotype-phenotype corr...

2016
Yuki Wada Satoshi Takahashi Makoto Koga Katsuhito Seki Manabu Hashimoto

Most pancreaticoduodenal artery aneurysms involve celiac trunk stenosis or occlusion. Few cases have been related to superior mesenteric artery (SMA) stenosis, and none of these was treated with SMA angioplasty before transcatheter arterial embolization (TAE) or operative resection of the aneurysm. We treated a 79-year-old woman with incidentally detected inferior pancreaticoduodenal artery ane...

Journal: :Journal of clinical pathology 1976
G F Bottazzo A Florin-Christensen A Fairfax G Swana D Doniach U Groeschel-Stewart

Three hundred and twelve sera containing antibodies to smooth muscle (SMA) wer analysed for the immunofluorescence patterns they produced in various tissues. A classification is described based on the three main appearances in rat kidney. Some sera, mainly of low titre, reacted only with vessel walls (SMA-V), some stained vessels and renal glomeruli (SMA-G) and high titre sera, mainly from pati...

2013
M. G. Rashed R. Ahsan T. K. Parnell

Both the Super-Elastic and Shape Memory Effect has been taken into account in this study by using SMA with high activation temperature. A Thermo-Mechanical SMA phenomenological constitutive model is used to simulate the SMA behaviour. The dynamic response data of a frame structure has been obtained from FE analysis by using the nonlinear FE software program MSC Marc. Then the frame is braced an...

Journal: :Muscle & nerve 2015
Aga Lewelt Kristin J Krosschell Gregory J Stoddard Cindy Weng Mei Xue Robin L Marcus Eduard Gappmaier Louis Viollet Barbara A Johnson Andrea T White Donata Viazzo-Trussell Philippe Lopes Robert H Lane John C Carey Kathryn J Swoboda

INTRODUCTION Preliminary evidence in adults with spinal muscular atrophy (SMA) and in SMA animal models suggests exercise has potential benefits in improving or stabilizing muscle strength and motor function. METHODS We evaluated feasibility, safety, and effects on strength and motor function of a home-based, supervised progressive resistance strength training exercise program in children wit...

2013
Jason Tipples Victoria Brattan Pat Johnston

The current research was designed to establish whether individual differences in timing performance predict neural activation in the areas that subserve the perception of short durations ranging between 400 and 1600 milliseconds. Seventeen participants completed both a temporal bisection task and a control task, in a mixed fMRI design. In keeping with previous research, there was increased acti...

Background & Aims: Spinal muscular atrophy (SMA) is a common disorder with autosomal recessive inheritance pattern. The frequency of carriers of this disease is one in forty to one in sixty. SMA occurs in 98% of cases due to the homozygous deletion of SMN1 exons 7 and 8. The purpose of this study was to evaluating the deletion and point mutations of the SMN1 gene in patients with SMA in west Az...

1998
WILLIAM T. CLOWER GARRETT E. ALEXANDER

Clower, William T. and Garrett E. Alexander. Movement semovements precede, or follow, X . Here we present evidence quence-related activity reflecting numerical order of components that the numerical order of specific components may also in supplementary and presupplementary motor areas. J. Neurobe represented by movement sequence-related activity of physiol. 80: 1562–1566, 1998. The supplementa...

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