Impaired trophoblast invasion is associated with pregnancy disorders such as early pregnancy loss and preeclampsia. There is evidence to suggest that the consumption of caffeine during pregnancy may increase the risk of pregnancy loss; however, little is known about the direct effect of caffeine on normal trophoblast biology. Our objectives were to examine the effect of caffeine on trophoblast ...

BACKGROUND Heparin can significantly reduce pregnancy complications in women with certain thrombophilias, such as antiphospholipid syndrome. Recent reports suggest that heparin may act by mechanisms other than anticoagulation. However, the effect of heparin on trophoblast biology in the absence of thrombophilia has not been extensively investigated. Therefore, this study aimed to evaluate troph...

BACKGROUND AND PURPOSE The endovascular treatment (EVT) of intracranial aneurysms is no more limited by the presence of a branch at the neck or by the neck width. Saccular aneurysms with a branch arising from the sac, however, are mostly candidates for surgery rather than embolization. We prospectively evaluated the feasibility and safety of the EVT in such cases. METHODS Between May and Nove...

BACKGROUND AND PURPOSE Ischemic stroke is the most common complication after surgical clipping of anterior choroidal artery (AChA) aneurysms, and the reported morbidity-mortality rates vary from 5% to 50%. We report the findings in a series of 18 consecutive patients who underwent endovascular treatment (EVT) for an AChA berry aneurysm. METHODS In this retrospective study, the aneurysms were ...

Abstract Background/Introduction Endovascular thrombectomy (EVT) has become the standard of care for management acute ischaemic stroke, but risk intracerebral haemorrhage and mortality still remains common following stroke. The effect concomitant atrial fibrillation (AF) on clinical outcomes in patients with stroke after receiving EVT unclear. Purpose To investigate associations between AF (ICH...

Background Intravenous thrombolysis (IVT) and endovascular therapy (EVT) are both important treatments for large‐vessel occlusion stroke. However, it is still unclear how the timing of IVT, EVT, need transfer a patient to an stroke center EVT affect outcomes. In this investigation, we study interaction between rapidity among patients with Methods This investigation analysis OPUS‐REACH (Optimizi...

Early recanalization of occluded vessels in patients with acute ischemic stroke (AIS) by either intravenous thrombolysis (IVT) or endovascular revascularization has been shown to be associated with improved clinical outcomes and reduced mortality. Since the initial report regarding endovascular treatment (EVT) of AIS in 1983, endovascular techniques have been tremendously improved, advancing fr...

The extreme events of floods, rainfalls, waves, and wind often cause serious damage. observed data can be used to detect the sign abnormal phenomena prevent crucial Anomaly detection techniques, techniques distinguishing between normal cases from data, have been one most methods for detecting suspicious collected data. Although many anomaly appeared in literature, almost all them are based on m...