BACKGROUND We aimed to assess the recent incidence trends of ectopic pregnancies (EP) in France (1992-2002). METHODS A population-based register of all women aged 15-44 years with EP was set up in Auvergne (central France). We calculated rates of EP as a 'reproductive failure' or as a 'contraceptive failure', frequencies of exposure to the two main risk factors for EP (cigarette smoking and c...

Purpose: The current study investigates the preferred psychotropic drug treatments and their tolerability in elderly patients (EP) with a diagnosis of schizophrenia or schizoaffective disorder compared to younger (YP).
 Materials Methods: included 154 EP 195 YP schizophrenia/schizoaffective admitted outpatient unit at university hospital last decade. medical records were reviewed. types do...

Enhancer mapping has been greatly facilitated by various genomic marks associated with it. However, little is available in our toolbox to link enhancers with their target promoters, hampering mechanistic understanding of enhancer–promoter (EP) interaction. We develop and characterize multiple genomic features for distinguishing true EP pairs from noninteracting pairs. We integrate these feature...

Let X be a compact connected Riemann surface and EP a holomorphic principal P–bundle over X , where P is a parabolic subgroup of a complex reductive affine algebraic group G. If the Levi bundle associated to EP admits a holomorphic connection, and the reduction EP ⊂ EP × P G is rigid, we prove that EP admits a holomorphic connection. As an immediate consequence, we obtain a sufficient condition...

We investigated the role of the prostaglandin E(2) (PGE(2)) EP(1) receptor in modulating urine concentration as it is expressed along the renal collecting duct where arginine-vasopressin (AVP) exerts its anti-diuretic activity, and in the paraventricular and supraoptic nuclei of the hypothalamus where AVP is synthesized. The urine osmolality of EP(1)-null mice (EP(1)(-/-)) failed to match level...

INTRODUCTION The response to exogenous epinephrine (Ep) is difficult to predict given the multitude of factors involved such as broad pharmacokinetic and pharmacodynamic between-subject variabilities, which may be more pronounced in children. We investigated the pharmacokinetics and pharmacodynamics of Ep, co-administered with milrinone, in children who underwent open heart surgical repair for ...

BACKGROUND Adolescents born extremely preterm (EP; <28 weeks' gestation) and/or extremely low birthweight (ELBW; <1000 g) experience high rates of visual impairments, however the potential neural correlates of visual impairments in EP/ELBW adolescents require further investigation. This study aimed to: 1) compare optic radiation and primary visual cortical structure between EP/ELBW adolescents ...

The present studies report erythropoietin (Ep) production in primary cultures of a human renal carcinoma from a patient with erythrocytosis that has been serially transplanted to BALB/c nude mice. The levels of erythropoietin in the culture media were estimated using the exhypoxic polycythemic mouse assay (EHPCMA), fetal mouse liver erythroid colony-forming technique (FMLC), and a radioimmunoas...

The ability of a variety of affinity adsorbents to isolate erythropoietin (Ep) from contaminating proteins in crude preparetions of the hormone was examined. Of 3 lectin-agarose derivatives, 6 bound Ep but only 2, wheat germ agglutinin (WGA) and phytohemagglutinin (PHA), bound the hormone quantitatively. The extent to which PHA bound Ep depended on the isolectin composition of the PHA. The leuk...

The aim of this study was to compare how respiratory compensation point (RCP) and end-test power (EP) change in response to the same four-week high intensity interval training (HIIT). The power output associated with RCP and EP before and after HIIT were recorded in 24 recreationally active participants (14 men and 10 women). RCP was determined from an incremental exercise test and EP was deriv...