We investigated the contribution of large conductance calcium-activated potassium (BK) channels to spontaneous activity of cerebellar Purkinje neurons in mice and rats. In Purkinje neurons which fire tonically, block of BK channels increased the firing rate and caused the neurons to fire irregularly. In Purkinje neurons which exhibited a trimodal pattern of activity, present primarily in mature...

The decision to recruit manpower in an organization requires clear identification of the criteria (attributes) that distinguish successful from unsuccessful performance. The choice of appropriate attributes or criteria in different levels of hierarchy in an organization is a multi-criteria decision problem and therefore multi-criteria decision making (MCDM) techniques can be used for prioritiza...

CA1 pyramidal cells receive two major excitatory inputs; the perforant path (PP) terminates in the most distal dendrites whereas the Schaffer collateral (SC) terminates more proximally. We have examined the mechanism of the afterhyperpolarization (AHP) that follows single subthreshold EPSPs in these inputs. The AHPs were not reduced by a GABA A antagonist or by agents that block Ca 2+ entry. Ap...

Application of model base in group decision making that makes up a Group Decision Support System (GDSS) is of paramount importance. Analytic Hierarchy Process (AHP) is the multi-criteria decision making (MCDM) that has been applied in GDSS. In order to be effectively used in GDSS, AHP needs to be customized so that it is more user friendly with ease of used features. In this paper, we propose a...

Analytic Hierarchy Process (AHP) is one of the most popular method in the field of decision-making today. While there exist many kinds of extensions of AHP using fuzzy measures or fuzzy sets, one of the most natural uses of fuzzy sets is to employ a reciprocal matrix with fuzzy-valued entries. Indeed, using classical AHP, there is often not enough consistency among the data due to strong condit...

This article presents a literature review of the applications of Analytic Hierarchy Process (AHP). AHP is a multiple criteria decision-making tool that has been used in almost all the applications related with decision-making. Out of many different applications of AHP, this article covers a select few, which could be of wide interest to the researchers and practitioners. The article critically ...

Financial problems have been the subject of much research. A widely used approach in recent work on these problems is the use of fuzzy set theory, where fuzzy terms are used to model the uncertain environments. The purpose of this work is to combine the fuzzy analytic hierarchy process (AHP) with the portfolio selection problem. More specifically, the decision-making problem is to decide which ...

The descending contralateral movement detector (DCMD) is a high-performance interneuron in locusts with an axon capable of transmitting action potentials (AP) at more than 500 Hz. We investigated biophysical mechanisms for fidelity of high-frequency transmission in this axon. We measured conduction velocities (CVs) at room temperature during exposure to 10 mmol/L cadmium, a calcium current anta...

This study explored the antioxidant potential and anti-fatigue effects of polyphenols extracted from Areca Catechu L. husk (AHP). Radicals scavenging activities and reducing power were determined to evaluate the antioxidant potentials in vitro and a weight loaded forced swimming test (WFST) was used to estimate the anti-fatigue effect. The main components of AHP were analyzed by HPCE at last. T...

Managing natural resource lands requires social, as well as biophysical, considerations. Unfortunately, it is extremely difficult to accurately assess and quantify changing social preferences, and to aggregate conflicting opinions held by diverse social groups. The Analytic Hierarchy Process (AHP) provides a systematic, explicit, rigorous, and robust mechanism for eliciting and quantifying subj...