نتایج جستجو برای: مدل پذیرش تکنولوژی tam
تعداد نتایج: 150389 فیلتر نتایج به سال:
Long-term tamoxifen (TAM) therapy was examined in athymic mice bearing MCF-7 tumors of different sizes. Six months of TAM treatment caused no increase in tumor size (compared to placebo treatment) for animals treated initially following implantation of tumor pieces (approximately 1 mm3) or for animals with 0.2-cm2 tumors (grown with 1 month of estrogen treatment). Tumors could be regrown with e...
Tamoxifen (TAM), an estrogen receptor antagonist used primarily to treat breast cancer, has well-recognized antifungal properties, but the activity of TAM has not been fully characterized using standardized (i.e., CLSI) in vitro susceptibility testing, nor has it been demonstrated in an in vivo model of fungal infection. In addition, its mechanism of action remains to be clearly defined at the ...
Long-term tamoxifen (TAM) therapy was examined in athymic mice bearing MCF-7 tumors of different sizes. Six months of TAM treatment caused no increase in tumor size (compared to placebo treatment) for animals treated initially following implantation of tumor pieces (approx imately 1 mm3) or for animals with 0.2-cm2 tumors (grown with 1 month of estrogen treatment). Tumors could be regrown with ...
Tualang honey (TH) is rich in flavonoids and phenolic acids and has significant anticancer activity against breast cancer cells comparable to the effect of tamoxifen (TAM), in vitro. The current study evaluated the effects of TH when used in combination with TAM on MCF-7 and MDA-MB-231 cells. We observed that TH promoted the anticancer activity of TAM in both the estrogen receptor-(ER-)responsi...
Tamoxifen (TAM) is a selective estrogen receptor modulator (SERM) used in the treatment of breast cancer; however many women complain of weight gain during TAM treatment. The anorectic effects of estradiol (E) and TAM are well known, although the effects of E on the consumption of palatable food are controversial and there is no information regarding the effects of TAM on palatable food consump...
پژوهش حاضر با بسط نظریه مدل پذیرش فنّاوری (tam)3 ، نظریه رفتار برنامه ریزی شده (tpb)4 و عامل اعتماد، به مطالعه و بررسی عوامل اثرگذار بر استفاده از فنّاوری اطلاعات و اینترنت در بخش بانکداری در ایران به ویژه بانکداری اینترنتی از سوی مشتریان در بانک ملت ایران، پرداخته است. یکی از نظریه هایی که مورد توجه بسیاری از پژوهشگران قرار گرفته است، مدل پذیرش فنّاوری ارائه شده توسط دیویس است (davis 1986). وی مع...
هدف این مطالعه تجزیه و تحلیل پذیرش برنامههای حسابداری توسط دانشجویان این رشته است که با استفاده از مدل پذیرش فناوری (TAM) صورت گرفته است. این پژوهش به بررسی رفتار دانشجویان با استفاده از متغیرهای سهولت مشاهده شده در استفاده، سودمندی مشاهده شده و استفاده از سیستم، میپردازد. نمونهی این تحقیق شامل 141 دانشجوی حسابداری استان اصفهان بودند که از برنامههای حسابداری استفاده میکردند. نحوهی جمعآور...
BACKGROUND AND OBJECTIVE Tumor-associated macrophage (TAM) infiltration promotes the progression of various malignancies. This study was to investigate the influence of TAM infiltration on the survival and prognosis of patients with ovarian cancer. METHODS The expression of CD68, a TAM-specific marker, in 67 specimens of ovarian cancer and 22 specimens of benign ovarian lesion was detected by...
BACKGROUND Tamoxifen (TAM) is a nonsteroidal antiestrogen that has been widely used in the treatment of breast cancer through its anti-estrogen activity. Recent studies show that TAM is cytotoxic to both estrogen receptor (ER)-positive and ER-negative cells via the induction of apoptosis. However, the molecular mechanisms of this effect are not well understood. In the present study, we investig...
The major metabolites of tamoxifen (tam) formed by animal and human liver microsomes are mono-N-demethylated tam, 4-hydroxy-tam (4-OH-tam), and tam-N-oxide. The N-desmethylated-tam and 4-OH-tam are formed by P450s, whereas the N-oxide is primarily formed by flavin-containing monooxygenase. Because 4-OH-tam is a highly potent antiestrogen (and possibly is the active anticancer tam metabolite) an...
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