MTBE is found in water supplies used for drinking and other purposes. These experiments follow up on earlier reports of reproductive tract alterations in male mice exposed orally to MTBE and explored oxidative stress as a mode of action. CD-1 mice were gavaged with 400-2000 mg/kg MTBE on days 1, 3, and 5, injected i.p. with hCG (2.5 IU/g) on day 6, and necropsied on day 7. No effect was seen in...

The current investigation was conducted to report on the phytotoxicity of methyl tert-butyl ether (MTBE) to common bean (Phaseolus vulgaris L. cv. Nebraska) plants. The two-week-old potted plants were subjected to four weekly soil applications of aqueous MTBE concentrations (0, 1, 10, 25 and 50 ml L(-1)). The root growth, flower and pod development were more sensitive to MTBE treatments; while,...

Methyl tert-butyl ether (MTBE) is widely used as an oxygenating agent in gasoline to reduce harmful emissions. However, previous studies have demonstrated that MTBE is a cytotoxic substance that has harmful effects in vivo and in vitro. Although remarkable progress has been made in elucidating the mechanisms underlying the MTBE‑induced reproductive toxicological effect in different cell lines, ...

ether (MTBE) determination in specific groundwater matrices. It demonstrates the importance of laboratory selection for compound analysis based upon technical experience and instrument capabilities. This method study was performed in support of a treatment technology demonstration for MTBE conducted under the EPA Superfund Innovative Technology Evaluation program. MTBE is an oxygenate added to ...

The initial reactions in the cometabolic oxidation of the gasoline oxygenate, methyl tert-butyl ether (MTBE), by Mycobacterium vaccae JOB5 have been characterized. Two products, tert-butyl formate (TBF) and tert-butyl alcohol (TBA), rapidly accumulated extracellularly when propane-grown cells were incubated with MTBE. Lower rates of TBF and TBA production from MTBE were also observed with cells...

The environmental fate and biological effects of the fuel oxygenate methyl-tertiary-butyl ether (MTBE) is of concern because, among other factors, it is highly soluble in water. Thus ground and surface water contamination may occur through accidental exposures and spills. Little is known about the biodegradability and ecotoxicity of MTBE. We found that MTBE added to carbon-limited microbial con...