Dodd, J. S., J. A. Raleigh, and T. S. Gross. Osteocyte hypoxia: a novel mechanotransduction pathway. Am. J. Physiol. 277 (Cell Physiol. 46): C598–C602, 1999.—Bone is a unique tissue in which to examine mechanotransduction due to its essential role in weight bearing. Within bone, the osteocyte is an ideal cellular mechanotransducer candidate. Because osteocytes reside distant from the blood supp...

RAGAVENDRA R. BALIGA,1 DAVID R. PIMENTAL,1 YOU-YANG ZHAO,2 WILLIAM W. SIMMONS,1 MARK A. MARCHIONNI,3 DOUGLAS B. SAWYER,1 AND RALPH A. KELLY1 1Cardiovascular Division, Brigham and Women’s Hospital and Harvard Medical School, Boston 02115; 3Cambridge Neurosciences, Cambridge, Massachusetts 02139; and 2Department of Medicine, University of California at San Diego School of Medicine, La Jolla, Cali...

DOUGLAS R. SEALS, EDITH T. STEVENSON, PAMELA P. JONES, CHRISTOPHER A. DESOUZA, AND HIROFUMI TANAKA (With the Technical Assistance of Cyndi Long and Mary Jo Reiling) Human Cardiovascular Research Laboratory, Center for Physical Activity, Disease Prevention, and Aging, Department of Kinesiology and Applied Physiology, University of Colorado, Boulder 80309, and Department of Medicine, Divisions of...

PATRICK PAYAN, ANAICK EDEYER, HÉLÈNE DE PONTUAL, GIL BORELLI, GILLES BOEUF, AND NICOLE MAYER-GOSTAN Laboratoire de Physiologie et Toxicologie Environnementales, EA 2138; Laboratoire de Physiologie Cellulaire et Moléculaire, Centre National de la Recherche Scientifique, UMR 6548; Université de Nice-Sophia Antipolis, Faculté des Sciences, 06108 Nice Cedex; and Laboratoire de Sclérochronologie des...

Sakai, Hiroshi, Fumitaka Ikomi, and Toshio Ohhashi. Effects of endothelin on spontaneous contractions in lymph vessels. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H459–H466, 1999.—A mode of action of endothelin (ET) on spontaneous contractions was investigated in ring preparations of isolated bovine mesenteric lymphatics. ET-1 at concentrations between 10210 and 1029 M caused a dose-depende...

Wang, Jinjuan, and James C. Rose. Developmental changes in renal renin mRNA half-life and responses to stimulation in fetal lambs. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R1130–R1135, 1999.—In the perinatal period there is increased renin gene expression in the kidney compared with other stages of development. This may be related to changes in responsiveness of the renin...

Stevens, Randel J., Jeffery S. Weinert, and Nelson G. Publicover. Visualization of origins and propagation of excitation in canine gastric smooth muscle. Am. J. Physiol. 277 (Cell Physiol. 46): C448–C460, 1999.—The origin and spread of excitation were visualized with fluo 3 fluorescence in tissues isolated from canine gastric antrum. Sheets of circular muscle (5 3 6 mm) had at least 1 (30%) and...

Firth, Bruce T., Ingrid Belan, David J. Kennaway, and Robert W. Moyer. Thermocyclic entrainment of lizard blood plasma melatonin rhythms in constant and cyclic photic environments. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R1620–R1626, 1999.—We assessed how chronic exposure to 6-h cryophase temperatures of 15°C in an otherwise 33°C environment entrains the rhythm of blood ...

De Paula, Patrı́cia M., Jaci A. Castania, Leni G. H. Bonagamba, Hélio C. Salgado, and Benedito H. Machado. Hemodynamic responses to electrical stimulation of the aortic depressor nerve in awake rats. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R31–R38, 1999.—Changes in mean arterial pressure (MAP), heart rate (HR), and vascular resistance (hindquarter and mesenteric territori...

Burgess, Don E., Tabitha A. Zimmerman, Marshall T. Wise, Sheng-Gang Li, David C. Randall, and David R. Brown. Low-frequency renal sympathetic nerve activity, arterial BP, stationary ‘‘1/f noise,’’ and the baroreflex. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R894–R903, 1999.—The object of this study is to quantify the very low frequency (i.e., ,0.1 Hz) interactions between...