نتایج جستجو برای: قرارداد epc

تعداد نتایج: 13840  

Journal: :Journal of lipid research 2008
Daming Tang Jonathan Lu Jeffrey P Walterscheid Hsin-Hung Chen David A Engler Tatsuya Sawamura Po-Yuan Chang Hazim J Safi Chao-Yuh Yang Chu-Huang Chen

Endothelial progenitor cells (EPCs), important for endothelial regeneration and vasculogenesis, are reduced by cigarette smoking. To elucidate the mechanisms, we examined the effects of electronegative LDL, circulating in chronic smokers, on EPC differentiation. Using ion-exchange chromatography, we purified smoker LDL into five subfractions, L1-L5. In matched, nonsmoking healthy subjects, L5, ...

Journal: :The American naturalist 2010
Jon E Brommer Jussi S Alho Clotilde Biard Joanne R Chapman Anne Charmantier Amelie Dreiss Ian R Hartley Mårten B Hjernquist Bart Kempenaers Jan Komdeur Toni Laaksonen Paula K Lehtonen Thomas Lubjuhn Samantha C Patrick Balázs Rosivall Joost M Tinbergen Marco van der Velde Kees van Oers Tomasz Wilk Wolfgang Winkel

In many socially monogamous animals, females engage in extrapair copulation (EPC), causing some broods to contain both within-pair and extrapair young (EPY). The proportion of all young that are EPY varies across populations and species. Because an EPC that does not result in EPY leaves no forensic trace, this variation in the proportion of EPY reflects both variation in the tendency to engage ...

2012
Xu Song Yu Jiang Chunjuan Ren Xun Sun Qiang Zhang Tao Gong Zhirong Zhang

BACKGROUND The clinical application of nimodipine (NIM) is limited by several unfavorable properties, which are induced by its low aqueous solubility. In the present study, nimodipine-loaded egg phosphatidylcholine-sodium glycocholate mixed micelles (NIM-EPC-SGC-MMs) were prepared to improve the water solubility of NIM, thus allowing it to be more applicable for clinical use. METHODS NIM-EPC-...

Journal: :Diabetes 2007
Thomas Thum Daniela Fraccarollo Maximilian Schultheiss Sabrina Froese Paolo Galuppo Julian D Widder Dimitrios Tsikas Georg Ertl Johann Bauersachs

Uncoupling of the endothelial nitric oxide synthase (eNOS) resulting in superoxide anion (O(2)(-)) formation instead of nitric oxide (NO) causes diabetic endothelial dysfunction. eNOS regulates mobilization and function of endothelial progenitor cells (EPCs), key regulators of vascular repair. We postulate a role of eNOS uncoupling for reduced number and function of EPC in diabetes. EPC levels ...

2013
Chien-Yi Hsu Po-Hsun Huang Chia-Hung Chiang Hsin-Bang Leu Chin-Chou Huang Jaw-Wen Chen Shing-Jong Lin

BACKGROUND Recent research indicates hypertensive patients with microalbuminuria have decreased endothelial progenitor cells (EPCs) and increased levels of endothelial apoptotic microparticles (EMP). However, whether these changes are related to a subsequent decline in glomerular filtration rate (GFR) remains unclear. METHODS AND RESULTS We enrolled totally 100 hypertensive out-patients with ...

Introduction: Metabolic syndrome is defined as a cluster of metabolic disorders, which may lead to type II diabetes and cardiovascular diseases. Promotion of healthy lifestyle and use of herbal supplements with anthocyanin and phenols are recommended for the treatment of metabolic syndrome. The present study aimed to investigate the effects of eight weeks of combined aerobic an...

Journal: :Epilepsy & behavior : E&B 2009
Alexander Rotenberg Erica Hyunji Bae Masanori Takeoka Jose M Tormos Steven C Schachter Alvaro Pascual-Leone

OBJECTIVE Repetitive transcranial magnetic stimulation (rTMS) is a technique for noninvasive focal brain stimulation by which small intracranial electrical currents are generated by a fluctuating extracranial magnetic field. In clinical epilepsy, rTMS has been applied most often interictally to reduce seizure frequency. Less often, rTMS has been used to terminate ongoing seizures, as in instanc...

Journal: :Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2010
Kivanc Atesok Ru Li Duncan J Stewart Emil H Schemitsch

The objective of this study was to evaluate the effects of local endothelial progenitor cell (EPC) therapy on bone regeneration in a rat model. A segmental bone defect (5 mm) was created in the femur and fixed with a mini-plate. There were two groups: EPC-treated (N = 28) and control (N = 28). Seven animals were sacrificed from each group at 1, 2, 3, and 10 weeks postoperatively. Healing of the...

Journal: :American journal of physiology. Endocrinology and metabolism 2011
Ji Chen Shuzhen Chen Yusen Chen Cheng Zhang Jinju Wang Wenfeng Zhang Gang Liu Bin Zhao Yanfang Chen

For determining the implications of circulating endothelial progenitor cells (cEPCs) and cellular membrane microparticles (MPs) in diabetic stroke, levels of EPCs, EPC-MPs, and endothelium-derived MPs (EMPs) and their correlations with blood glucose concentration, cerebral microvascular density (cMVD), and ischemic damage were investigated in type 2 diabetic db/db and db/+ (wild-type control) m...

2013
Mohd Izwan Zainol Kamaruddin Mohd Yusoff Mohd Yasim Mohd Yusof

BACKGROUND Antibacterial activity of honey is mainly dependent on a combination of its peroxide activity and non-peroxide components. This study aims to investigate antibacterial activity of five varieties of Malaysian honey (three monofloral; acacia, gelam and pineapple, and two polyfloral; kelulut and tualang) against Staphylococcus aureus, Bacillus cereus, Escherichia coli, and Pseudomonas a...

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