Insomnia is a common sleep disorder which is prevalent in women and the elderly. Current insomnia drugs mainly target the γ-aminobutyric acid (GABA) receptor, melatonin receptor, histamine receptor, orexin, and serotonin receptor. GABAA receptor modulators are ordinarily used to manage insomnia, but they are known to affect sleep maintenance, including residual effects, tolerance, and dependenc...

The alcoholic extract of the bark of Zizyphus jujuba possesses antinociceptive, anticonvulsand and anti-inflammatory activities. The CNS depressant activity of the plant might be responsible, to some extent for these activities.

population. Current pharmacological approaches focus primarily on the g-aminobutyric acid (GABA)-ergic system, the major inhibitory neurotransmitter system of the central nervous system (CNS). Drugs that enhance synaptic GABA-ergic neurotransmission are widely utilized in the clinical setting for their sedative or hypnotic effects. Several classes of compounds—GABA, benzodiazepines, barbiturate...

Air pollution is a global environmental issue, and there an urgent need for sustainable remediation techniques. Thus, phytoremediation has become popular approach to air remediation. This paper reviewed 28 eco-friendly indigenous plants based on both the tolerance index (APTI) anticipated performance (API), using level indices evaluate potential of most plant species control. The estimated APTI...

Background: Medicinal plants have gained prime importance in treating several fatal diseases, such as cancer, diabetes, and eczema, because they are a rich source of bioactive phytochemicals safer alternative to synthesized chemical compounds. Genus Ziziphus Mill. belongs the family Rhamnaceae, which comprises 100 accepted plant species is well known for multipurpose applications food, fodder, ...

Atherogenic dyslipidemia, characterized by an increased level of lipoprotein (a) and a decreased level of adiponectin, is a major risk factor for cardiovascular diseases in diabetic patients. To reduce cardiovascular risk in diabetic patients, use of agents with antidiabetic and anti-atherogenic potential is required. Using an animal model of diabetes, we investigated the antiatherogenic potent...