Cellular adhesion to the extracellular matrix is mediated by a diverse class of alpha/beta heterodimeric receptors known as integrins, which transduce signals to activate multiple intracellular signal transduction pathways within the cells. The signaling pathway linking integrins to mediate neuronal process outgrowth is not well understood. Here, we have provided evidence that intracellular sig...

The role of calcium-activated chloride channels for renal function is unknown. By immunohistochemistry we demonstrate dominant expression of the recently identified calcium-activated chloride channels, Anoctamin 1 (Ano1, TMEM16A) in human and mouse proximal tubular epithelial (PTE) cells, with some expression in podocytes and other tubular segments. Ano1-null mice had proteinuria and numerous l...

This study aims to analyze the factors that influence financial performance of basic and chemical industrial companies listed on Indonesia Stock Exchange (IDX) in 2016-2020. research method is descriptive quantitative. The sample selection technique uses a purposive sampling so 20 obtained. data analysis path or using SMART-PLS application. results show coefficient value indicated by Financial ...

Peer-to-peer (P2P) Data-sharing systems now generate a significant portion of internet traffic. P2P systems have emerged as a popular way to share huge volumes of data. Requirements for widely distributed information systems supporting virtual organizations have given rise to a new category of P2P systems called schemabased. In such systems each peer is a database management system in itself, e...

Based on the stimulus–organism–response (SOR) model, purpose of current study is to investigate two types privacy concerns, i.e., concern abuse (PCA) and finding (PCF), in relation online collaborative learning (OCL). Further, another aim knowledge-sharing perceptions (KSP) as a mechanism between PCA PCF with OCL. A survey was used collect data from postgraduate university students Pakistan. Th...

Face recognition is important in human identification. The biological recognition technique acts as a good method and broad applications in security areas. This work presents a method to improve the face recognition accuracy using a combination of Principal Component Analysis (PCA), and Wavelet Transform. Wavelet Transform is used to decompose the input image with different levels and rearrange...

Neurofilaments are essential for acquisition of normal axonal calibers. Several lines of evidence have suggested that neurofilament-dependent structuring of axoplasm arises through an "outside-in" signaling cascade originating from myelinating cells. Implicated as targets in this cascade are the highly phosphorylated KSP domains of neurofilament subunits NF-H and NF-M. These are nearly stoichio...

The Kolmogorov stochasticity parameter (KSP) is applied to quantify the degree of randomness (stochasticity) in the temperature maps of the Cosmic Microwave Background radiation maps. It is shown that the KSP for the WMAP5 maps is about twice as high as that of the simulated maps for the concordance ΛCDM cosmological model, implying that a randomizing effect exists that has not been taken into ...