How various layers of epigenetic repression restrict somatic cell nuclear reprogramming is poorly understood. The transfer of mammalian somatic cell nuclei into Xenopus oocytes induces transcriptional reprogramming of previously repressed genes. Here, we address the mechanisms that restrict reprogramming following nuclear transfer by assessing the stability of the inactive X chromosome (Xi) in ...

Using $448.1\times 10 ^6$ $\psi(3686)$ decays collected with the BESIII detector at BEPCII $e^+e^-$ storage rings, branching fractions and angular distributions of $\chi_{cJ}\to\Xi^-\bar{\Xi}^+$ $\Xi^0\bar{\Xi}^0$ $(J = 0, 1, 2)$ are measured based on a partial-reconstruction technique. The $\chi_{c1}\to\Xi^0\bar{\Xi}^0$ $\chi_{c2}\to\Xi^0\bar{\Xi}^0$ observed for first time statistical signifi...

ix Preface xi Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi Publications during doctorate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xii

in some long term studies, a series of dependent and possibly truncated life-times may be observed. suppose that the lifetimes have a common marginal distribution function. in left-truncation model, one observes data (xi,ti) only, when ti ≤ xi. under some regularity conditions, we provide a strong representation of the ßn estimator of ß = p(ti ≤ xi), in the form of an average of random variable...

A positive real interval, [a, b] can be partitioned into sub-intervals such that sub-interval widths divided by sub-interval ”‘average”’ values remains constant. That both Arithmetic Mean and Geometric Mean ”‘average”’ values produce constant ratios for the same log scale is the stated invariance proved in this short note. The continuous analog is briefly considered and shown to have similar pr...

In this article, we present a complete classification of the negative parity ${\mathrm{\ensuremath{\Xi}}}_{c/b}^{\ensuremath{'}}$ and ${\mathrm{\ensuremath{\Xi}}}_{c/b}$ $P$-wave states: seven belonging to $SU(3)$ flavor sextet antitriplet, calculation strong partial decay widths into ${^{2}\mathrm{\ensuremath{\Sigma}}}_{c}\overline{K}$, ${^{2}\mathrm{\ensuremath{\Xi}}}_{c}^{\ensuremath{'}}\ens...

Let A be a matrix whose columns X1, . . . , XN are independent random vectors in R. Assume that p-th moments of 〈Xi, a〉, a ∈ Sn−1, i ≤ N , are uniformly bounded. For p > 4 we prove that with high probability A has the Restricted Isometry Property (RIP) provided that Euclidean norms |Xi| are concentrated around √ n and that the covariance matrix is well approximated by the empirical covariance m...

The genes (xylA) encoding xylose isomerase (XI) from two Lactococcus lactis subsp. lactis strains, 210 (Xyl(-)) and IO-1 (Xyl(+)), were cloned, and the activities of their expressed proteins in recombinant strains of Escherichia coli were investigated. The nucleotide and amino acid sequence homologies between the xylA genes were 98.4 and 98.6%, respectively, and only six amino acid residues dif...

A prominent feature of plant cells is the rapid, incessant movement of the organelles traditionally defined as cytoplasmic streaming and attributed to actomyosin motility. We sequenced six complete Nicotiana benthamiana cDNAs that encode class XI and class VIII myosins. Phylogenetic analysis indicates that these two classes of myosins diverged prior to the radiation of green algae and land plan...

T he finding that humans with hereditary factor XI deficiency have relatively mild bleeding tendencies—yet are significantly protected against certain thrombotic diseases— has sparked considerable interest in factor XI/XIa as a target for novel antithrombotic treatments. In the classic waterfall description of blood coagulation, there are 2 ways to trigger the plasma clotting system: the tissue...