We have evaluated 4 radioiodinated mouse monoclonal anticarcinoembryonic antigen antibodies (MAbs) by using the GW-39 human colorectal tumor xenograft transplanted i.m. in immunocompetent hamsters to determine whether there were any differences in their tumor localization properties. Additional comparisons were made to affinity-purified goat anticarcinoembryonic antigen antibody. Statistically ...

Oxygen reduction reaction (ORR) is investigated on bulk PdO-based catalysts (oxides of Pd and Pd3Co) in oxygen-saturated 0.1 M HClO4 to establish the role of surface oxides and adsorbed hydrogen in the activity and product selectivity (H2O/H2O2). The initial voltammetric features suggest that the oxides are inactive toward ORR. The evolution of the ORR voltammograms and potential-dependent H2O2...

Hollow nanomaterials have attracted a lot of interest by virtue of their wide range of applications that arise primarily due to their unique architecture. A common strategy to synthesize hollow nanomaterials is by nucleation of the shell material over a preformed core and subsequent dissolution of the core in the second step. Herein an ultrafast, microwave route has been demonstrated, to synthe...

Chiral oxazoline based bi and hexadentate ligands built on cyclophosphazene cores have been synthesized and characterized. (NPPh2)2[NP(m-OC6H4C(O)OCH3)2] (1) was prepared by the reaction of gem-(NPPh2)2(NPCl2) with methyl-3-hydroxy benzoate in the presence of Cs2CO3. Compound 1 was converted to the dicarboxylic acid (NPPh2)2[NP(m-OC6H4C(O)OH)2] (2) by base promoted hydrolysis with KO(t-Bu). The...

Among the economically viable and ecologically acceptable solutions for the safe disposal of waste glycerol coming from biodiesel production, the biotechnological conversion of glycerol into a very high-value-added bioplastic raw material, namely 1,3 propanediol (1,3-PDO) seems to be very promising. This process is easy and environmentally friendly since it produces no toxic wastes. The results...

Introduction Pycnodysostosis (PDO) is a rare autosomal recessive lysosomal storage disease of the bone caused by a mutation in a gene mapped to chromosome 1q21 that codes for the enzyme cathepsin K (CTSK). Pycnodysostosis (Greek: pycnos = dense; dys = defective; osteon = bone) was first coined in 1962 by Maroteaux and Lamy [1], although the first case fitting the description may have been repor...

The thyroid gland is an organ primarily composed of endoderm-derived follicular cells. Although disturbed embryonic development of the thyroid gland leads to congenital hypothyroidism in humans and mammals, the underlying principles of thyroid organogenesis are largely unknown. In this study, we introduce zebrafish as a model to investigate the molecular and genetic mechanisms that control thyr...

The concept of pseudodifferential operators (PDO) is introduced as a generalization of the usual concepts of differential and integral operators. Based on the PDO concept in Euclidean spaces the concept of a PDO on a manifold is developed. It is demonstrated that for PDOs on a manifold the main part of the operator coincides with the usual planar approximation of the operator. The so-called Mei...

Yields of protons emitted in the D + D reaction in Pd and PdO thick targets were measured for bombarding energies between 2.5 and 10 keV. The obtained yields were compared with those predicted by using the parameterization of cross sections at higher energies. It was found that both of the yields for Pd and PdO are surprisingly larger than the prediction. The bombarding energy dependence of the...