Epidermal growth factor receptor (EGFR) overexpression and activation result in increased proliferation and migration of solid tumors including ovarian cancer. In recent years, mounting evidence indicates that EGFR is a direct and functional target of miR-7. In this study, we found that miR-7 expression was significantly downregulated in highly metastatic epithelial ovarian cancer (EOC) cell li...

B A C K F I R E ? In late June, Hong Kong media reported China’s PLA-AF (People’s Liberation Army – Air Force) would seek to become a ‘strategic air force’ with the acquisition of the Russian Backfire cited as a core tenet of this fundamental policy change. To best appreciate the potential strategic impact of the Backfire upon the Asia Pacific region it is worth exploring the capabilities of th...

This note describes possible world semantics for a constructive modal logic CK. The system CK is weaker than other constructive modal logics K as it does not satisfy distribution of possibility over disjunctions, neither binary (3(A ∨ B) → 3A ∨ 3B) nor nullary (3⊥ → ⊥). Our intuition is that 3⊥ should not constructively imply ⊥, thus we dispense with both forms of distribution. We are intereste...

Certain types ofmacro-CK, type 1, have been reported to cause false increases in CK-MB by co-migration on electrophoresis (1-3). I report two such cases in which the macroCK was an IgA with anti-CK-BB specificity. According to methods proposed by Medeiros et al. (1), immunoprecipitation and subsequent analysis by elecrophoresis was used to separate interfering macre-CK from CK-MB. CK electropho...

Partindo da análise das manifestações de insatisfação usuários do Spotify no Twitter com o resultado Retrospectiva 2019, pretende-se investigar como a atuação dos algoritmos nas plataformas streaming música pode agenciar prática sonora ouvintes, tendo gosto musical um principais marcadores fruição ambiente digital. O artigo promove resgate conceito performance e busca repensá-lo partir dinâmica...

Serum creatine kinase isoenzyme 2 concentrations (CK 2 mass) were measured in marathon runners during training and 1 and 2 days after a race and compared with values from 36 acute myocardial infarction (AMI) patients whose total CK and (or) CK 2 activities were similar to those of runners in the basal state. During training, runners had CK and CK 2 activities 53% and 43% above reference values,...