Protein arginine methylation is a widespread post-translational modification (PTM) in eukaryotic cells. This chemical proteins functionally modulates diverse cellular processes from signal transduction, gene expression, DNA damage repair,...

Three distinct forms of replication factor C are known to play vital roles in genome replication and integrity in eukaryotic cells. A fourth such complex has recently been identified; initial results suggest that this new family member plays an important role during S phase.