In the last decades we found many data concerning the association between a hypercoagulable state and its causes and adverse pregnancy outcome, in particular recurrent pregnancy loss (RPL). Although first studies were focused only on the association between thrombophilia and RPL, subsequent studies underlined also a potential role of antithrombotic treatment to prevent vascular complication suc...

Background Recurrent pregnancy loss (RPL) is usually defined as three or more consecutive pregnancy losses before 20th gestational week. Many etiological factors have been considered as cause of RPL including genetic factors, uterine anatomical defects, endocrine abnormalities, thrombotic and immunologic factors. Nevertheless, the cause of RPL remains unknown in around half of the patients desp...

background: recurrent pregnancy loss (rpl) is defined as two or more miscarriages before the 20 th week of gestation and its etiology is unknown in 50% of the cases. interleukin 6 is an immune mediator, plays a regulatory role in embryo implantation and placental development. objective: the purpose was to assess the association between il-6 -634c/g polymorphism and, susceptibility to idiopathic...

BACKGROUND Recurrent pregnancy loss (RPL) has been defined as two or more miscarriages before 20(th) week of gestation. It seems that IL-27 may reduce inflammatory responses and affect the survival of the embryo during human pregnancy. IL-27 polymorphisms may influence RPL by altering the levels or the activity of gene product. OBJECTIVE We studied for the first time the association of IL-27 ...

BACKGROUND Recurrent pregnancy loss (RPL), defined as 3 or more consecutive miscarriages, is widely attributed either to repeated chromosomal instability in the conceptus or to uterine factors that are poorly defined. We tested the hypothesis that abnormal cyclic differentiation of endometrial stromal cells (ESCs) into specialized decidual cells predisposes to RPL, based on the observation that...

The next generation of electric grid has a scalable and reliable bi-directional communication infrastructure known as Advanced Metering Infrastructure (AMI) to allow monitoring and controlling of grid resources. In this kind of communication system, comprising thousands of resource-constrained nodes such as smart meters, the routing protocol plays a critical role to guarantee reliability and lo...

The routing protocol for low power and lossy networks (RPL) was recently designed in the ROLL working group at IETF. Few simulation tools exist that enable its evaluation in order to prepare for its real deployment. In this paper, we provide a new evaluation of this protocol with two approaches using two different simulators adapted to our needs. We first evaluated the value of mobile sinks in ...