Bcl-2 interacting cell death suppressor (Bis), also known as Bag3 or CAIR-1, is involved in antistress and antiapoptotic pathways. In addition to Bcl-2, Bis binds to several proteins, suggesting it has diverse functions in normal and pathological conditions. To better define the physiological function of Bis in vivo, we developed bis-deficient mice with a cre-loxP system. Targeted disruption of...

INTRODUCTION Bispectral index (BIS) and state entropy (SE) are prone to artifacts, especially due to electrocautery (EC). We compared the incidence of artifacts in BIS and SE during surgery under local anesthesia and sedation. METHODS 28 females undergoing breast surgery under local anesthesia and sedation were studied. Simultaneous BIS and SE measurements were recorded every 10 seconds. Arti...

The synthesis of novel bis(3-carbazoly1)methane linked bis-benzimidazoles is described. Construction symmetrical on the bis-carbazolylmethane scaffold was succeeded by condensation reaction benzene-1,2-diamine derivatives with bis(9-ethyl-9H-carbazole-3-carbaldehyde). structural analysis targeted compounds 4-7 were confirmed NMR, FT-IR spectroscopy and mass spectrometry. thermal stability final...

in this paper, two double helical dinuclear copper(ii) complexes of bis-n,o-bidentate schiff base ligands bis(3-methoxy-n-salicylidene-4,4'-diaminodiphenyl)sulfone (l1) and bis(5-bromo-n-salicylidene-4,4'-diaminodiphenyl)sulfone (l2) were prepared and characterized by elemental analyses (chn), as well as thermal analysis. elemental analyses (chn) suggested that the reaction between ligands and ...

A series of bis-BODIPYs 1-6 bridged via thiophene, furan, N-alkylcarbazole, triphenyl-amine, para- and meta-phenylene groups have been synthesized and characterized by various spectroscopic techniques. The change in the spectroscopic properties of bis-BODIPYs upon varying the size of spacers was studied. X-ray crystal structures of three bis-BODIPYs containing triphenylamine, para- and meta-phe...

The behavioral inhibition system (BIS) and behavioral approach system (BAS) are thought to influence sensitivity to reinforcement and punishment, making them useful for predicting mood-related drinking outcomes. This study provided the first examination of BIS and BAS as moderators of longitudinal within-person associations between mood and alcohol-related consequences in college student drinke...

Reaction of nitrobenzyl alcohol with glucose (200 mol%) in the presence NaOH water-ethanol medium gave 1,2-bis(4-(hydroxymethyl)phenyl)diazene oxide, 1,2-bis(2-(hydroxymethyl)phenyl)diazene oxide and 1,2-bis(4-(1-hydroxyethyl)phenyl)diazene 76%, 76% 72% yields, respectively.