Scutellaria baicalensis Georgi (SBG) is a traditional Chinese herbal medicine used to clear fever, release fire, neutralize poison, stop bleeding and prevent miscarriage in the form of decoction or extracts. It is confirmed that the active components of the root of SBG are flavonoids which have anti-inflammatory and anti-allergic effects, antioxidant, anti-thrombotic and vasoprotective properti...

Seagrass meadows are highly productive and ecologically important habitats in estuaries and coastal lagoons, and contain a variety of faunal communities, from which the caridean shrimps are a dominant component. The purpose of this work was to analyze the environmental parameters of water and sediments, with the biological components in seagrass epifaunal communities, from the Western Gulf of M...

We evaluated the antioxidant properties of four main flavones from Scutellaria baicalensis: baicalein, wogonin and their glucuronides - baicalin and wogonoside. We used three in vitro assays: free radical scavenging with 2,2'-diphenylpicrylhydrazyl radical, transition metal ions reducing power by phosphomolybdenum assay and inhibition of the hydroxyl radical-induced peroxidation of linoleic aci...

OBJECTIVES In this study we examined the in vitro synergistic effect of baicalin, the flavone constituent of Scutellaria spp., in combinations with oxytetracycline and tetracycline on the growth of Staphylococcus aureus. METHODS The MICs were determined by the broth microdilution method and the effect of combinations was evaluated according to the sum of fractional inhibitory concentration in...

Gastrodin (GAS) is one of the rare traditional Chinese medicinal materials in our country and it has been widely used in the treatment of cardiovascular and cerebrovascular diseases. Baicalein is a traditional Chinese herbal medicine, the active ingredient of Scutellaria baicalensis Georgi has a wide range of pharmacological effects. in recent years Fan Jinghui et al found that baicalein has a ...

The essential oil of Scutellaria barbata was obtained by hydrodistillation with a 0.3% (v/w) yield and analysed by GC and GC-MS. The main compounds in the oil were hexahydrofarnesylacetone (11.0%), 3,7,11,15-tetramethyl-2-hexadecen-1-ol (7.8%), menthol (7.7%) and 1-octen-3-ol (7.1%). The antimicrobial activity of the oil was evaluated against 17 microorganisms using disc diffusion and broth mic...

Chalcones, which have characteristic 1,3-diaryl-2-propen-1-one skeleton, are mainly produced in roots, rhizomes, heartwood, leaves, and seeds of genera Angelica, Sophora, Glycyrrhiza, Humulus, Scutellaria, Parartocarpus, Ficus, Dorstenia, Morus, Artocarpus, and so forth. They have become of interest in the research and development of natural antitumor agents over the past decades due to their b...

OBJECTIVE To investigate the effects of Scutellaria barbata extract (ESB) in suppressing tumor growth and modulating the immune functions in mice bearing tumors derived from hepatocarcinoma H22 cells. METHODS Fifty mice inoculated subcutaneously with H22 cells were equally divided into the model group, high-, moderate-, and low-dose ESB groups, and 5-Fu group, with corresponding treatments fo...

The content of flavonoids especially baicalin and baicalein determined the medical quality of Scutellaria baicalensis which is a Chinese traditional medicinal plant. Here, we investigated the mechanism responsible for the content and composition of flavonoids in S. baicalensis under water deficit condition. The transcription levels of several genes which are involved in flavonoid biosynthesis w...