نتایج جستجو برای: تیوری ri

تعداد نتایج: 12020  

2015
A Suri S Chapel C Lu K Venkatakrishnan

Physiologically based pharmacokinetic (PBPK) modeling and classical population pharmacokinetic (PK) model-based simulations are increasingly used to answer various drug development questions. In this study, we propose a methodology to optimize the development of drugs, primarily cleared by the kidney, using model-based approaches to determine the need for a dedicated renal impairment (RI) study...

2015
Chao Li Dayi Hu Xubo Shi Li Li Jingang Yang Li Song Changsheng Ma

BACKGROUND Numerous previous studies have shown that renal insufficiency (RI) in patients with acute coronary syndrome is associated with poor cardiovascular outcomes. These studies do not well address the impact of RI on the long-term outcome of patients with acute ST-elevation myocardial infarction (STEMI) in China. The aim of this study was to investigate the association of admission RI and ...

2014
Jonas Emil Sabroe Per Thayssen Lisbeth Antonsen Mikkel Hougaard Knud Nørregaard Hansen Lisette Okkels Jensen

BACKGROUND Chronic kidney disease is associated with increased risk of mortality. We examined the impact of moderate and severe renal insufficiency (RI) on short- and long-term mortality among unselected patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). METHODS From January 1, 2002 to December 31, 2010 all patients ...

2014
Giulio G. Stefanini Masanori Taniwaki Bindu Kalesan Lorenz Räber Stefan Stortecky Thomas Pilgrim Yoshinobu Onuma Sigmund Silber Patrick W. Serruys Bernhard Meier Peter Jüni Stephan Windecker

BACKGROUND Renal impairment (RI) is associated with impaired prognosis in patients with coronary artery disease. Clinical and angiographic outcomes of patients undergoing percutaneous coronary intervention (PCI) with the use of drug-eluting stents (DES) in this patient population are not well established. METHODS We pooled individual data for 5,011 patients from 3 trials with the exclusive an...

2015
Zhuo Liang Xiang-min Shi Li-feng Liu Xin-pei Chen Zhao-liang Shan Kun Lin Jian Li Fu-kun Chen Yan-guang Li Hong-yang Guo Yu-tang Wang

BACKGROUND A close association exists between renal impairment (RI) and atrial fibrillation (AF) occurrence. Increased activity of the sympathetic nervous system (SNS) may contribute to the development of AF associated with RI. Renal denervation (RDN) decreases central sympathetic activity. OBJECTIVE The main objective of the study was to explore the effects of RDN on AF occurrence and its po...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1997
J Riehl H Schmitt D Bongartz D Bergmann H G Sieberth

BACKGROUND Detection of renal artery stenoses (RAS) by means of duplex Doppler ultrasound with direct scanning of the main renal arteries is subject to numerous limitations. Using semiquantitative analysis of the Doppler curve, which can be recorded from intrarenal arteries, it is possible to detect RAS unaffected by the problems of direct Doppler scanning of the renal arteries. METHODS Both ...

ﺩﺭ ﺩﺍﺩﻩﻫﺎی EEG/MEG، ﺁﺭﺗﻴﻔﻜﺖ ﻫﺪﺍﻳﺖ ﺣﺠﻤﻰ ﺑﻪ ﺻﻮﺭﺕ ﺗﺮﻛﻴﺐ ﺧﻄﻰ ﻟﺤﻈﻪﺍی ﻓﻌﺎﻟﻴﺖ ﻣﻨﺎﺑﻊ ﻣﻐﺰی ﺩﺭ ﻛﺎﻧﺎﻝﻫﺎ ﻣﺸﺎﻫﺪﻩ ﻣﻰﺷﻮﺩ. ﻳﻜﻰ ﺍﺯ ﻭﻳﮋﮔﻰﻫﺎی ﻣﻬﻢ ﺗﺨﻤﻴﻦﮔﺮﻫﺎی ﺍﻳﺪﻩﺁﻝ ﺍﺭﺗﺒﺎﻃﺎﺕ ﻣﻐﺰی، ﻣﻘﺎﻭﻣﺖ ﺑﻪ ﺁﺭﺗﻴﻔﻜﺖ ﻫﺪﺍﻳﺖ ﺣﺠﻤﻰ ﺍﺳﺖ؛ ﻳﻌﻨﻰ ﻫﺪﺍﻳﺖ ﺣﺠﻤﻰ ﻣﻨﺎﺑﻊ ﻣﻐﺰی ﻣﺴﺘﻘﻞ ﻫﺮﮔﺰ ﻧﺒﺎﻳﺪ ﻣﻨﺠﺮ ﺑﻪ ﺗﺨﻤﻴﻦ ﺍﺭﺗﺒﺎﻃﺎﺕ ﻣﻌﻨﻰﺩﺍﺭی ﺑﻴﻦ ﻛﺎﻧﺎﻝﻫﺎی EEG/MEG ﺷﻮﺩ. ﺗﺎﻛﻨﻮﻥ ﻫﻴﭻ ﻣﻌﻴﺎﺭی ﺑﺮﺍی ﻣﻘﺎﻳﺴﻪ ﺳﻄﺢ ﻣﻘﺎﻭﻣﺖ ﺗﺨﻤﻴﻦﮔﺮﻫﺎی ﻣﺨﺘﻠﻒ ﺍﺭﺗﺒﺎﻃﺎﺕ ﻣﻐﺰی ﺩﺭ ﻣﻘﺎﺑﻞ ﺁﺭﺗﻴﻔﻜﺖ ﻫﺪﺍﻳﺖ ﺣﺠﻤﻰ ﺩ...

Journal: :Chest 2003
Kai M Beeh Jutta Beier Oliver Kornmann Annette Mander Roland Buhl

STUDY OBJECTIVES Neutrophilic inflammation is a major feature of COPD. Induced sputum is increasingly used to monitor inflammatory airway diseases. Although short-term repeatability of selected sputum markers has been extensively studied in several populations, data on the long-term repeatability of induced sputum markers in stable COPD are scant. DESIGN Sputum supernatant of 12 patients with...

Journal: :IEEE Trans. Automat. Contr. 2000
Shaosheng Zhou Gang Feng Sing Kiong Nguang

From the coordinates transformation, we can see that only after i 1 (ri 1 (t)) is obtained can hi (ri (t )) be obtained. After we obtain hi (ri (t )) ; ~ ij (rj (t )) can be determined from (6). In other words, ~ ij (rj (t )) can not be determined until i 1 (ri 1 (t)) is obtained. However, from the iterative procedure in the main result of [1], we can see that function i 1 (ri 1 (t)) is obtaine...

Journal: :Int. J. Imaging Systems and Technology 1998
Stephane Tramini Marc Antonini Michel Barlaud

HVSLWH DGYDQFHV LQ WKH GRPDLQ RI VRXUFH FRGLQJ OLWWOH UHFHQW ZRUN KDV EHHQ GHYRWHG WR WKH SUREOHP RI MRLQW FRGLQJ DQG GHFRGLQJ ,Q SDUWLFXODU WKH GHVLJQ RI GHFRGHUV KDV EHHQ WR RXU NQRZOHGJH OLWWOH LQYHVWLJDWHG ,Q WKLV SDSHU ZH IRFXV RQ GHFRGLQJ IRU LQWUDIUDPH LPDJHV RI YLGHR GDWD ,Q RXU DSSURDFK ZH SURSRVH D QHZ PHWKRG IRU GHFRGLQJ E\ QRQOLQHDU ILOWHULQJ +HUH ZH EUHDN ZLWK WKH XVXDO DSSURDFK RI...

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