INTRODUCTION Interictal brain single photon emission computed tomography (SPECT) is used in the presurgical evaluation of patients with complex partial epilepsy. The aim of the present study was to compare interictal SPECT, MRI and video-electroencephalography (EEG) for seizure focus localization in patients with temporal lobe epilepsy, one year after temporal lobectomy, in order to determine t...

UNLABELLED With an increasing emphasis on quantitation of SPECT imaging and its use in dosimetry to guide therapies, it is desirable to understand the repeatability in normal-organ SPECT uptake values (SPECT-UVs). We investigated the variability of normal abdominal organ uptake in repeated (111)In-pentetreotide SPECT studies. METHODS Nine patients with multiple (111)In-pentetreotide SPECT/CT ...

BACKGROUND Facet joint disease plays a major role in axial low-back pain. Few diagnostic tests and imaging methods for identifying this condition exist. Single photon emission computed tomography (SPECT) is reported that it has a high sensitivity and specificity in diagnosing facet disease. We prospectively evaluated the use of bone scintigraphy with SPECT for the identification of patients wit...

Objective: The aim of this study was to evaluate the influences of reconstruction and attenuation correction on the differences in the radioactivity distributions in 123I brain SPECT obtained by the hybrid SPECT/CT device. Methods: We used the 3-dimensional (3D) brain phantom, which imitates the precise structure of gray mater, white matter and bone regions. It was filled with 123I solution (20...

Introduction Quality control is an important phenomenon in nuclear medicine imaging. A Jaszczak SPECT Phantom provides consistent performance information for any SPECT or PET system. This article describes the simulation of a Jaszczak phantom and creating an executable phantom file for comparing assessment of SPECT cameras using SIMIND Monte Carlo simulation program which is well-established fo...

Introduction: In this study the evaluation of a Platelet-based Maximum Penalized Likelihood Estimation (MPLE) for denoising SPECT images was performed and compared with other denoising methods such as Wavelets or Butterworth filtration. Platelet-based MPLE factorization as a multiscale decomposition approach has been already proposed for better edges and surfaces representation due to Poi...

Introduction: Meningioma is usually a benign brain tumor, but sometimes with aggressive course. The aim of this study was to assess the ability of 201Tl Brain SPECT to differentiate the pathologic grade of meningioma preoperatively. Methods: Thirty lesions in 28 patients were evaluated in this study. Early (20 minutes) and late (3 hours) brain SPECT images were performed and early u...

Planar ventilation-perfusion (V/Q) scanning is often used to investigate pulmonary embolism; however, it has well-recognized limitations. SPECT overcomes many of these through its ability to generate 3-dimensional imaging data. V/Q SPECT has higher sensitivity, specificity, and accuracy than planar imaging and a lower indeterminate rate. SPECT allows for new ways to display and analyze data, su...

Single Photon Emission Computed Tomography (SPECT) provides a potential to perform in vivo quantification of the radioactivity and dose distributions in the process of evaluating radiopharmaceuticals. The inherent modest resolution in SPECT impedes the potential of accurate quantification. Previously, we investigated a joint estimation approach for combining SPECT functional information with hi...

We studied the radioisotope iodine-123-iodoamphetamine ([123I]IMP) and its performance in single-photon emission computed tomographic (SPECT) studies of cerebral blood flow (CBF). In seven normal volunteers, IMP/SPECT CBF measurements were calculated using a two-compartment model and were compared with the results of CBF measurements utilizing (O15)-H2O and positron emission tomography (PET). C...