The early stages of human lymphopoiesis are poorly characterized. Here, we compared the lymphoid potential of a novel umbilical cord blood CD34(+)CD45RA(hi)CD7(+) hematopoietic progenitor cell (HPC) population with that of CD34(+)CD45RA(hi)Lin(-)CD10(+) HPCs, previously proposed as candidate common lymphoid progenitors. Limiting-dilution and clonal analysis, fetal thymic organ cultures, and cul...

Hypoxia ischemia (HI) is a recognized risk factor among late-preterm infants, with HI events leading to varied neuropathology and cognitive/behavioral deficits. Studies suggest a sex difference in the incidence of HI and in the severity of subsequent behavioral deficits (with better outcomes in females). Mechanisms of a female advantage remain unknown but could involve sex-specific patterns of ...

Hypoxic-ischemic (HI) encephalopathy occurs in approximately 6 per 1000 term newborns leading to devastating neurological consequences, such as cerebral palsy and seizures. Maternal smoking is one of the prominent risk factors contributing to HI injury. Mitochondrial integrity plays a critical role in neural injury and repair during HI. We previously showed that maternal cigarette smoke exposur...

The aim of this retrospective study was to analyze the concomitant prevalence rates for lactose malabsorption (LM), fructose malabsorption (FM), and histamine intolerance (HI) in patients with so far unexplained gastrointestinal (GI) symptoms. A total of 439 outpatients, who presented unclear abdominal discomfort, underwent lactose (50 g) and fructose (25 g) hydrogen (H2) breath tests. Addition...

We present a deep VLA search for HI emission from the low-luminosity Virgo Cluster elliptical galaxy NGC 4476, which contains 1.1×10 8 M ⊙ of molecular gas in an undisturbed disk in regular rotation. No HI was detected. The rms noise in the final image corresponds to a 3σ column density sensitivity of 1.2×10 20 cm −2 at the position of NGC 4476, averaged over the 4 kpc beam. The total HI mass i...

Postischemic seizures are associated with worsened outcome following stroke, but the underlying pathophysiology is poorly understood. Here we examined acute seizures in adult mice following hypoxia-ischemia (HI) via combined behavioral, electrophysiological, and histological assessments. C57BL/6 mice aged 4-9 months received a permanent occlusion of the right common carotid artery and then unde...

One gets more than two hundred papers when searching by the keywords “Hardy” and “inequality” in the review journals Zentralblatt für Mathematik or Mathematical Reviews. Almost half of these publications appeared after 1990. In the absolute majority, these papers deal with various generalizations, extensions and improvements of the wellknown Hardy inequality (HI) presented in monograph [8] (bot...

1 Department of Oceanography, University of Hawai‘i at Mānoa, Honolulu, HI, United States, 2 Pacific Islands Fisheries Science Center, National Oceanic and Atmospheric Administration, Honolulu, HI, United States, 3 Department of Biology, University of Hawai‘i at Mānoa, Honolulu, HI, United States, 4 Joint Institute for Marine and Atmospheric Research, University of Hawai‘i at Mānoa, Honolulu, H...

1Okinawa International University, Okinawa 901-2701, Japan 2Okinawa Research Center for Longevity Science, Okinawa 901-2114, Japan 3Pacific Health Research and Education Institute, Honolulu, HI 96813, USA 4Department of Research, Kuakini Medical Center, Honolulu, HI 96817, USA 5Department of Research, Planning and Development, The Queen’s Medical Center, Honolulu, HI 96813, USA 6Department of G...