Cerebral microangiopathy (CMA) has been associated with executive dysfunction and fronto-parietal neural network disruption. Advances in magnetic resonance imaging allow more detailed analyses of gray (e.g., voxel-based morphometry-VBM) and white matter (e.g., diffusion tensor imaging-DTI) than traditional visual rating scales. The current study investigated patients with early CMA and healthy ...

We study the local minima relocation of the fractionally spaced Constant Modulus Algorithm(FSE-CMA) cost function in the presence of noise. Local minima move in a particular direction as the noise power increases and their number may be eventually reduced. In such cases the performance of FSE-CMA may fail to adequately reduce inter symbol interference (ISI), but achieve an approximated MMSE by ...

OBJECTIVE To study the association between analfissures and cow's milk allergy (CMA) in infants. METHODS AND METHOD: In a prospective study, 72 confirmed cases of CMA in infants were examined for anal fissure by pediatricians with five years' experience. A positive finding was defined as when an anal fissure was detected by at least two out of three examiners. RESULTS Of infants with CMA with...

The nature and evolutionary state of the diverse objects displaying the B[e] phenomenon are reasonably known, except for a rare subtype named FS CMa stars. These are surrounded by compact disks of warm dust whose origin is unclear. Although the luminosity of these objects corresponds to main-sequence stars, mass loss rates derived from emission lines are 2 orders of magnitude larger than predic...

Taking inspiration from approximate ranking, this paper investigates the use of rank-based Support Vector Machine as surrogate model within CMA-ES, enforcing the invariance of the approach with respect to monotonous transformations of the fitness function. Whereas the choice of the SVM kernel is known to be a critical issue, the proposed approach uses the Covariance Matrix adapted by CMA-ES wit...

Two obese patients with sleep apnea syndrome were administered chlormadinone acetate (CMA), a synthetic progesterone, known as a potent respiratory stimulant to augment load compensation response as well as CO2 chemosensitivity. Before CMA administration, both cases showed normal chemosensitivity of hypoxic and hypercapnic ventilatory responses (HVR and HCVR) at daytime, although marked oxygen ...

Based on evolutionary computation techniques, we present a parallel, globally convergent, multiobjective optimization algorithm which extends the Covariance Matrix Adaptation Evolutionary Strategy (CMA-ES). This approach enables identifying multiple global optima and multiple discontinuous Pareto set solutions of the optimization problem in a compact search space. After evaluating the algorithm...

In this study, we consider simulation-based worst-case optimization problems with continuous design variables and a finite scenario set. To reduce the number of simulations required increase restarts for better local optimum solutions, propose new approach referred to as adaptive subset selection (AS3). The proposed subsamples support construct objective function in given neighborhood, introduc...