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1 PAPERS IN THIS THESIS 2

Partial sequencing of the 16S-23S rDNA intergenic spacer showed two to four genotypes each for Borrelia hermsii and B. turicatae, both relapsing fever agents transmitted by argasid ticks, and for B. miyamotoi and B. lonestari, transmitted by ixodid ticks. Field surveys of Ixodes ticks in Connecticut and Sweden showed limited local diversity for B. miyamotoi.

Immunological cross-reactivity has been shown between related genera of the family Treponemataceae. Extracts of Borrelia cross-react with antibodies in syphilitic serum (Saurino and De Lamater, 1952) and produce positive skin tests in the later stages of syphilis (Ranque, Quilici, and Assadourian, 1967). The fluorescent treponemal antibody absorption test (FTA-ABS) is at present considered to b...

Railivay Hospital, Hubli, M. and S. M. Railway. Th? following cases of relapsing fever were admitted to this hospital during a local epidemic in August to October 1923. Some of them might have been mistaken for plague, had not the diagnosis been confirmed in each instance by the finding of spirochetes in blood films:? Case 1, aet. 27.?Admitted to hospital for continuous fever for 6 days, slight...

Previous studies revealed that the heart suffers significant injury during experimental Lyme and relapsing fever borreliosis when the immune response is impaired (D. Cadavid, Y. Bai, E. Hodzic, K. Narayan, S. W. Barthold, and A. R. Pachner, Lab. Investig. 84:1439-1450, 2004; D. Cadavid, T. O'Neill, H. Schaefer, and A. R. Pachner, Lab. Investig. 80:1043-1054, 2000; and D. Cadavid, D. D. Thomas, ...

BACKGROUND In the United States, Tick-Borne Relapsing Fever (TBRF) in dogs is caused by the spirochete bacteria Borrelia turicatae and Borrelia hermsii, transmitted by Ornithodoros spp. ticks. The hallmark diagnostic feature of this infection is the visualization of numerous spirochetes during standard blood smear examination. Although the course of spirochetemia has not been fully characterize...

We conducted repeat muscle MR imaging (figure) on a 46-yearold man with relapsing eosinophilic fasciitis that can be classified in a continuum around the so-called Shulman syndrome.1 The patient had a 6-month history of relapsing fever and pain and swelling of the lower limbs, which responded to a moderate dosage of corticosteroids but relapsed several times after tapering of corticosteroids. I...

Relapsing fever borreliae require lipid compounds for growth in vitro. In this study, the major pathways of lipid catabolism in three species of tick-borne relapsing fever borreliae were investigated. Thin-layer chromatography was used to compare chloroform-methanol extracts of fresh culture media with extracts of exhausted culture media after organisms were removed by centrifugation. The chrom...